Apoptosis signal-regulating kinase 1 plays a pivotal role in angiotensin II-induced cardiac hypertrophy and remodeling.

Circ Res. 2003 Oct 31;93(9):874-83. Epub 2003 Oct 9.

Apoptosis signal-regulating kinase 1 plays a pivotal role in angiotensin II-induced cardiac hypertrophy and remodeling.

Izumiya Y, Kim S, Izumi Y, Yoshida K, Yoshiyama M, Matsuzawa A, Ichijo H, Iwao H.

Department of Pharmacology, Osaka City University Graduate School of Medical Science, 1-4-3 Asahimachi, Abeno, Osaka 545-8585, Japan.

http://www.ncbi.nlm.nih.gov/pubmed/14551246

http://circres.ahajournals.org/content/93/9/874.long

Fig.4A - "Wild" image is similar to  "ASK1 -/-". 
( Fig.4AのWildとASK1-/-の組織切片画像が類似。同一個体由来の組織切片のもので、スライス位置が違うだけと思われる。 )

J Am Soc Nephrol. 2003 Mar;14(3):584-92.

Differential contribution of three mitogen-activated protein kinases to PDGF-BB-induced mesangial cell proliferation and gene expression.

Kawano H, Kim S, Ohta K, Nakao T, Miyazaki H, Nakatani T, Iwao H.

Source

Department of Pharmacology, Osaka City University Medical School, Japan.

http://www.ncbi.nlm.nih.gov/pubmed/12595493

http://jasn.asnjournals.org/content/14/3/584.long

Fig.1C - Image of 3 lanes of "ERK" is similar to  that of "p38".

( Fig. 1CのERKの3レーンとp38の3レーンが類似。
濃さあるいはコントラストが変更されており、完全一致はしない。)

Important role of angiotensin II-mediated c-Jun NH(2)-terminal kinase activation in cardiac hypertrophy in hypertensive rats.

Hypertension. 2000 Oct;36(4):511-6.

Important role of angiotensin II-mediated c-Jun NH(2)-terminal kinase activation in cardiac hypertrophy in hypertensive rats.

Izumi Y, Kim S, Zhan Y, Namba M, Yasumoto H, Iwao H.

Department of Pharmacology, Osaka City University Medical School, Osaka 545-8585, Japan.

http://www.ncbi.nlm.nih.gov/pubmed/11040228

http://hyper.ahajournals.org/content/36/4/511.long

Fig.2 - The left lane of "ERK-Lo" in the Fig.2 is similar to  the right lane of "ERK-W" in Fig.4. 

( Fig.2 ERK-Lo 左列、Fig.4 ERK-W 右列が類似。 )

Circ Res. 1998 Oct 5;83(7):752-60.

Differential activation of cardiac c-jun amino-terminal kinase and extracellular signal-regulated kinase in angiotensin II-mediated hypertension.

Yano M, Kim S, Izumi Y, Yamanaka S (山中伸弥), Iwao H.

Source

Department of Pharmacology, Osaka City University Medical School, Osaka, Japan.

http://www.ncbi.nlm.nih.gov/pubmed/9758646

http://circres.ahajournals.org/content/83/7/752.long

Fig.1C - The lane of  "5min" is similar to  the horizontally flipped image of "3h" lane.

( Fig. 1Cの5 minと3hが、左右反転すると類似。一致はしない。 3hのp42ERKの左端の方にある白い帯はノイズだろうか。 )

Hypertension. 1998 Jan;31(1):50-6.

Cardiac mitogen-activated protein kinase activities are chronically increased in stroke-prone hypertensive rats.

Izumi Y, Kim S, Murakami T, Yamanaka S (山中伸弥), Iwao H.

Source

Department of Pharmacology, Osaka City University Medical School, Abeno, Osaka, Japan.

http://www.ncbi.nlm.nih.gov/pubmed/9449390

http://hyper.ahajournals.org/content/31/1/50.long

Fig.5 - The left lane and right lane of  "S (SHRSP)" of "24 wk" are similar. 

( Fig. 5の24 wk、S(SHRSP)の2レーンが、レーン間で類似。一致はしない。 

特に、p55 JNKとp46 JNKの間の部分の一部が左のレーンでは存在しない。 )