tag:blogger.com,1999:blog-20226125371513653012024-03-13T12:48:27.225+09:00光山勝慶グループ 論文疑惑疑惑1: 熊本大学大学院生命科学研究部(医学系)生体機能薬理学分野 光山勝慶教授
の論文の実験画像間における類似性について
疑惑2: 光山勝慶氏がEndopint committee memberを務めた降圧薬バルサルタン(ディオバン)の臨床研究Kyoto Heart Studyに、ノバルティスファーマ社の白橋伸雄氏が身分を隠蔽して統計解析に関与していたことが判明しています。組織ぐるみの詐欺的販売促進活動か?11jigenhttp://www.blogger.com/profile/03513633746083109180noreply@blogger.comBlogger12125tag:blogger.com,1999:blog-2022612537151365301.post-16617444555824136992013-05-18T22:36:00.002+09:002013-08-08T00:14:44.761+09:00論文疑惑まとめ<span style="font-size: large;">・ </span><a href="http://kim-mitsuyama-shokei.blogspot.com/2013/05/blog-post_18.html" style="font-size: x-large;">光山勝慶氏の経歴</a><span style="font-size: large;">(熊本大学教授)</span><br />
<span style="font-size: large;">・ <a href="http://kim-mitsuyama-shokei.blogspot.com/2013/05/blog-post.html">疑惑論文に関連する公的研究費、競争的資金まとめ</a></span><br />
<span style="font-size: large;">・ <a href="http://diovan-novartis.blogspot.com/2013/05/kyoto-heart-study.html">ノバルティス社ディオバンの臨床研究(Kyoto Heart Study)に関する疑惑</a></span><span style="font-size: large;">(利益相反問題の隠蔽)</span><br />
<span style="font-size: large;">・ 熊本大学、大阪市立大学、文部科学省に調査を依頼しました。</span><br />
<b style="background-color: white; color: #666666; font-family: 'Trebuchet MS', Trebuchet, Verdana, sans-serif; font-size: 13.333333969116211px; line-height: 20px;"><span style="color: red; font-family: Arial, Helvetica, sans-serif; font-size: medium;"><br /></span></b>
<b style="background-color: white; color: #666666; font-family: 'Trebuchet MS', Trebuchet, Verdana, sans-serif; font-size: 13.333333969116211px; line-height: 20px;"><span style="color: red; font-family: Arial, Helvetica, sans-serif; font-size: medium;">・電気泳動実験画像や組織画像について疑惑がある論文</span></b><br />
論文#1 <a href="http://kim-mitsuyama-shokei.blogspot.com/2013/05/calcium-channel-blockers-more-than.html">PLoS One. 2012;7(6):e39162.</a><br />
論文#2 <a href="http://kim-mitsuyama-shokei.blogspot.com/2013/05/advanced-glycation-end-products.html">Circulation. 2006 Mar 14;113(10):1353-60.</a><br />
論文#3 <a href="http://kim-mitsuyama-shokei.blogspot.com/2013/05/beneficial-effect-of-candesartan-on-rat.html">J Pharmacol Sci. 2005 Aug;98(4):372-9.</a><br />
論文#4 <a href="http://kim-mitsuyama-shokei.blogspot.com/2013/05/excess-aldosterone-under-normal-salt.html">Hypertens Res. 2005 May;28(5):447-55.</a><br />
論文#5 <a href="http://kim-mitsuyama-shokei.blogspot.com/2013/05/apoptosis-signal-regulating-kinase-1.html">Circ Res. 2003 Oct 31;93(9):874-83.</a><br />
論文#6 <a href="http://kim-mitsuyama-shokei.blogspot.com/2013/05/differential-contribution-of-three.html">J Am Soc Nephrol. 2003 Mar;14(3):584-92.</a><br />
論文#7 <a href="http://kim-mitsuyama-shokei.blogspot.com/2013/05/important-role-of-angiotensin-ii.html">Hypertension. 2000 Oct;36(4):511-6.</a><br />
論文#8 <a href="http://kim-mitsuyama-shokei.blogspot.com/2013/05/differential-activation-of-cardiac-c.html">Circ Res. 1998 Oct 5;83(7):752-60.</a><br />
論文#9 <a href="http://kim-mitsuyama-shokei.blogspot.com/2013/05/cardiac-mitogen-activated-protein.html">Hypertension. 1998 Jan;31(1):50-6.</a><br />
<br />
<br />
<b style="background-color: white; color: #666666; font-family: 'Trebuchet MS', Trebuchet, Verdana, sans-serif; font-size: 13.333333969116211px; line-height: 20px;"><span style="color: red; font-family: Arial, Helvetica, sans-serif; font-size: medium;">・疑惑の詳細</span></b><br />
論文#1<br />
PLoS One. 2012;7(6):e39162.<br />
<a href="http://kim-mitsuyama-shokei.blogspot.com/2013/05/calcium-channel-blockers-more-than.html">Calcium channel blockers, more than diuretics, enhance vascular protective effects of angiotensin receptor blockers in salt-loaded hypertensive rats.</a><br />
責任著者: <span style="color: red;">光山勝慶</span><br />
・ Fig.4(A)とFig.4(B)のTubulilnの左から2,3,4レーン目の画像(Ol, Az, Hy)が、Fig.4(C)のTubulinの左から1,2,3レーン目の画像(Ve, Ol, Az)に類似している。<br />
さらに、Fig.4(A)とFig.4(B)のTubulilnの左から5,6,7レーン目の画像(Ol+Ax, Ol+Hy, WKY)が、Fig.4(C)のTubulinの左から4,5,6レーン目の画像(Hy, Ol+Az, Ol+Hy)に類似している。<br />
Fig.4(A)とFig.4(B)のTubulinの左から4レーン目と5レーン目の間に編集の跡を見ることができる。<br />
さらに、Fig.4(C)のTubulinの左から3レーン目と4レーン目の間にも編集の跡を見ることができる。<br />
・ Fig.4(A)とFig.4(B)のTubulilnの左から2,3,4,5,6,7レーン目の画像(Ol, Az, Hy, Ol+Ax, Ol+Hy, WKY)が、Fig.4(D)とFig.5(B)のTubulinの左から1,2,3,4,5,6レーン目の画像(Ve, Ol, Az, Hy, Ol+Az, Ol+Hy)に類似している。<br />
<br />
論文#2<br />
Circulation. 2006 Mar 14;113(10):1353-60.<br />
<a href="http://kim-mitsuyama-shokei.blogspot.com/2013/05/advanced-glycation-end-products.html">Advanced glycation end products activate a chymase-dependent angiotensin II-generating pathway in diabetic complications.</a><br />
責任著者: <a class="name-search" href="http://circ.ahajournals.org/search?author1=Hui+Y.+Lan&sortspec=date&submit=Submit" style="background-color: white; border: 0px; color: #333333; font-family: inherit; font-size: inherit; font-style: inherit; line-height: inherit; margin: 0px; outline-style: none; padding: 0px; text-align: inherit; text-decoration: none; vertical-align: 0px; white-space: nowrap; word-wrap: break-word;">Hui Y. Lan</a>、共著者: <span style="color: red;">光山勝慶</span><br />
Fig.3(B)のGAPDHの画像が、Fig.4のGAPDHの画像に類似している。<br />
<br />
論文#3<br />
J Pharmacol Sci. 2005 Aug;98(4):372-9.<br />
<a href="http://kim-mitsuyama-shokei.blogspot.com/2013/05/beneficial-effect-of-candesartan-on-rat.html">Beneficial effect of candesartan on rat diastolic heart failure.</a><br />
責任著者: <span style="color: red;">光山勝慶</span><br />
Fig.4においてBNPの画像がMCP-1に類似している。<br />
<br />
論文#4<br />
Hypertens Res. 2005 May;28(5):447-55.<br />
<a href="http://kim-mitsuyama-shokei.blogspot.com/2013/05/excess-aldosterone-under-normal-salt.html">Excess aldosterone under normal salt diet induces cardiac hypertrophy and infiltration via oxidative stress.</a><br />
責任著者: <span style="color: red;">光山勝慶</span><br />
Fig.2Bにおいて、Conの画像がALD/Spiの画像に類似している。<br />
<br />
論文#5<br />
Circ Res. 2003 Oct 31;93(9):874-83.<br />
<a href="http://kim-mitsuyama-shokei.blogspot.com/2013/05/apoptosis-signal-regulating-kinase-1.html">Apoptosis signal-regulating kinase 1 plays a pivotal role in angiotensin II-induced cardiac hypertrophy and remodeling.</a><br />
責任著者: <span style="color: red;">光山勝慶</span><br />
Fig.4Aにおいて、Wildの画像が、ASK1-/-の画像に類似している。<br />
<br />
論文#6<br />
J Am Soc Nephrol. 2003 Mar;14(3):584-92.<br />
<a href="http://kim-mitsuyama-shokei.blogspot.com/2013/05/differential-contribution-of-three.html">Differential contribution of three mitogen-activated protein kinases to PDGF-BB-induced mesangial cell proliferation and gene expression.</a><br />
責任著者: <span style="color: red;">光山勝慶</span><br />
Fig.1Cにおいて、ERKの3レーン分の画像が、p38の3レーン分の画像に類似している。<br />
<br />
論文#7<br />
Hypertension. 2000 Oct;36(4):511-6.<br />
<a href="http://kim-mitsuyama-shokei.blogspot.com/2013/05/important-role-of-angiotensin-ii.html">Important role of angiotensin II-mediated c-Jun NH(2)-terminal kinase activation in cardiac hypertrophy in hypertensive rats.</a><br />
責任著者: <span style="color: red;">光山勝慶</span><br />
Fig.2のERK-Loの左列の画像が、Fig.4のERK-Wの右列の画像に類似している。<br />
<br />
論文#8<br />
Circ Res. 1998 Oct 5;83(7):752-60.<br />
<a href="http://kim-mitsuyama-shokei.blogspot.com/2013/05/differential-activation-of-cardiac-c.html">Differential activation of cardiac c-jun amino-terminal kinase and extracellular signal-regulated kinase in angiotensin II-mediated hypertension.</a><br />
Corresponding author: <span style="color: red;">光山勝慶</span>、共著者: <a href="http://yamanaka-shinya.blogspot.com/">山中伸弥</a><br />
Fig.1Cにおいて、5minのレーンの画像が、3hの画像を水平に反転させた画像に類似している。<br />
<br />
論文#9<br />
Hypertension. 1998 Jan;31(1):50-6.<br />
<a href="http://kim-mitsuyama-shokei.blogspot.com/2013/05/cardiac-mitogen-activated-protein.html">Cardiac mitogen-activated protein kinase activities are chronically increased in stroke-prone hypertensive rats.</a><br />
責任著者: <span style="color: red;">光山勝慶</span>、共著者: <a href="http://yamanaka-shinya.blogspot.com/">山中伸弥</a><br />
Fig.5において、24wkのS(SHRSP)の左列と右列の画像同士が類似している。<br />
<br />
<span style="color: #38761d;"><br /></span>
<br />
<hr style="background-color: white; color: #666666; font-family: arial, helvetica, clean, sans-serif; font-size: 0.8465em; line-height: 14.548611640930176px;" />
<h3 class="post-title entry-title" itemprop="name" style="background-color: white; color: #666666; font-family: 'Trebuchet MS', Trebuchet, Verdana, sans-serif; font-size: 22px; font-weight: normal; margin: 0.75em 0px 0px; position: relative;">
<a href="http://diovan-novartis.blogspot.com/2013/05/kyoto-heart-study.html">Kyoto Heart Study</a></h3>
<div class="post-header" style="background-color: white; color: #666666; font-family: 'Trebuchet MS', Trebuchet, Verdana, sans-serif; font-size: 11.111111640930176px; line-height: 1.6; margin: 0px 0px 1.5em;">
<div class="post-header-line-1">
</div>
</div>
<div class="post-body entry-content" id="post-body-5112855571346767177" itemprop="description articleBody" style="background-color: white; position: relative; width: 546.0069580078125px;">
<br />
<div class="cit" style="color: #666666; font-family: arial, helvetica, clean, sans-serif; font-size: 0.8465em; line-height: 1.45em;">
<span role="menubar"><span class="highlight">Eur Heart J</span>.</span> 2009 Oct;<span class="highlight">30</span>(20):<span class="highlight">2461</span>-9. doi: 10.1093/eurheartj/ehp363. Epub 2009 Aug 31.</div>
<h1 style="color: #666666; font-family: arial, helvetica, clean, sans-serif; font-size: 1.231em; line-height: 1.125em; margin: 0.375em 0px; position: relative;">
Effects of valsartan on morbidity and mortality in uncontrolled hypertensive patients with high cardiovascular risks: KYOTO HEART Study.</h1>
<div class="auths" style="color: #666666; font-family: 'Trebuchet MS', Trebuchet, Verdana, sans-serif; line-height: 1.4;">
<span style="font-family: arial, helvetica, clean, sans-serif; line-height: 23.33333396911621px;">Takahisa Sawada1*, Hiroyuki Yamada1, Bjo¨ rn Dahlo¨ f 2, and </span><a href="http://blog.goo.ne.jp/matsubaralaboratory" style="font-family: arial, helvetica, clean, sans-serif; line-height: 23.33333396911621px;">Hiroaki Matsubara</a><span style="font-family: arial, helvetica, clean, sans-serif; line-height: 23.33333396911621px;">1 (<a href="http://blog.goo.ne.jp/matsubaralaboratory">松原弘明</a>) for the KYOTO HEART Study Group </span></div>
<div class="auths">
<span style="color: #666666; font-family: arial, helvetica, clean, sans-serif;"><span style="line-height: 23.33333396911621px;">1 Department of Cardiovascular Medicine, Kyoto Prefectural University School of Medicine, Kajiicho 465, Kamigyoku, Kyoto 602-8566, Japan; and </span></span></div>
<div class="auths">
<span style="color: #666666; font-family: arial, helvetica, clean, sans-serif;"><span style="line-height: 23.33333396911621px;">2 Department of Medicine, Sahlgrenska University Hospital/ O¨ stra, Go¨ teborg, Sweden</span></span></div>
<div class="aff">
<h3 class="label" style="color: #724128; font-family: arial, helvetica, clean, sans-serif; font-size: 1.0769em; height: 1px; left: -10000px; line-height: 1.2857; margin: 1.2856em 0px 0.6428em; overflow: hidden; position: absolute; top: auto; width: 1px;">
ource</h3>
<div style="color: #666666; font-family: arial, helvetica, clean, sans-serif; font-size: 0.8465em; line-height: 1.0915em; margin-bottom: 0.5em; margin-top: 0.5em;">
<a href="http://www.ncbi.nlm.nih.gov/pubmed/19723695" style="color: #bb2188; font-size: 13.333333969116211px; line-height: 1.0915em; text-decoration: none;">http://www.ncbi.nlm.nih.gov/pubmed/19723695</a></div>
<div style="color: #666666; font-family: arial, helvetica, clean, sans-serif; font-size: 13.333333969116211px; line-height: 1.0915em; margin-bottom: 0.5em; margin-top: 0.5em;">
<a href="http://eurheartj.oxfordjournals.org/content/30/20/2461.long" style="color: #bb2188; line-height: 1.0915em; text-decoration: none;">http://eurheartj.oxfordjournals.org/content/30/20/2461.long</a><br />
<a href="http://eurheartj.oxfordjournals.org/content/30/20/2461.full.pdf" style="color: #bb2188; line-height: 1.0915em; text-decoration: none;">http://eurheartj.oxfordjournals.org/content/30/20/2461.full.pdf</a></div>
<div style="margin-bottom: 0.5em; margin-top: 0.5em;">
<div style="color: #666666; font-family: arial, helvetica, clean, sans-serif; font-size: 0.8465em; line-height: 1.0915em;">
<br /></div>
<div style="color: #666666; font-family: arial, helvetica, clean, sans-serif; font-size: 13.333333969116211px; line-height: 1.0915em;">
<b><span style="font-size: medium;"><a href="http://eurheartj.oxfordjournals.org/content/34/14/1023.long" style="color: #bb2188; text-decoration: none;">Retraction Notice</a></span></b></div>
<div>
<div style="color: #666666; font-family: arial, helvetica, clean, sans-serif; font-size: 0.8465em; line-height: 1.0915em;">
<blockquote class="tr_bq">
<span style="color: black; font-family: 'Lucida Grande', 'Lucida Sans Unicode', Tahoma, Verdana, Arial, Helvetica, sans-serif; font-size: 14px; line-height: 21px;">"This article has been retracted by the journal. Critical problems existed with some of the data reported in the above paper. The editors of the European Heart Journal hereby retract this paper and discourage citations of it.</span><span style="color: black; font-family: 'Lucida Grande', 'Lucida Sans Unicode', Tahoma, Verdana, Arial, Helvetica, sans-serif; font-size: 14.44444465637207px; line-height: 20.98958396911621px;">"</span></blockquote>
</div>
<div style="color: #666666; font-family: 'Trebuchet MS', Trebuchet, Verdana, sans-serif; font-size: 13.333333969116211px; line-height: 1.4;">
<br /></div>
<div style="color: #666666; font-family: 'Trebuchet MS', Trebuchet, Verdana, sans-serif; font-size: 13.333333969116211px; line-height: 1.4;">
<span style="font-family: arial, helvetica, clean, sans-serif;"><span style="font-size: 14px; line-height: 14.78125px;"><b>Conflict of interest:</b> the sponsor had no role in study design, data</span></span></div>
<div style="color: #666666; font-family: 'Trebuchet MS', Trebuchet, Verdana, sans-serif; font-size: 13.333333969116211px; line-height: 1.4;">
<span style="font-family: arial, helvetica, clean, sans-serif;"><span style="font-size: 14px; line-height: 14.78125px;">collection, data analysis, data interpretation, or writing of the report.</span></span></div>
<div style="color: #666666; font-family: 'Trebuchet MS', Trebuchet, Verdana, sans-serif; font-size: 13.333333969116211px; line-height: 1.4;">
<span style="font-family: arial, helvetica, clean, sans-serif;"><span style="font-size: 14px; line-height: 14.78125px;">The executive committee had full access to all the data at the end</span></span></div>
<div style="color: #666666; font-family: 'Trebuchet MS', Trebuchet, Verdana, sans-serif; font-size: 13.333333969116211px; line-height: 1.4;">
<span style="font-family: arial, helvetica, clean, sans-serif;"><span style="font-size: 14px; line-height: 14.78125px;">of the study, and has final responsibility for the decision to submit</span></span></div>
<div style="color: #666666; font-family: 'Trebuchet MS', Trebuchet, Verdana, sans-serif; font-size: 13.333333969116211px; line-height: 1.4;">
<span style="font-family: arial, helvetica, clean, sans-serif;"><span style="font-size: 14px; line-height: 14.78125px;">for publication.</span></span></div>
<div style="color: #666666; font-family: 'Trebuchet MS', Trebuchet, Verdana, sans-serif; font-size: 13.333333969116211px; line-height: 1.4;">
<span style="font-family: arial, helvetica, clean, sans-serif;"><span style="font-size: 14px; line-height: 14.78125px;"><br /></span></span><span style="font-family: arial, helvetica, clean, sans-serif;"><span style="font-size: 14px; line-height: 14.78125px;"><b>Endpoint committee</b></span></span></div>
<div style="color: #666666; font-family: 'Trebuchet MS', Trebuchet, Verdana, sans-serif; font-size: 13.333333969116211px; line-height: 1.4;">
<span style="font-family: arial, helvetica, clean, sans-serif;"><span style="font-size: 14px; line-height: 14.78125px;">Jitsuo Higaki, Department of Integrated Medicine and Informatics,</span></span></div>
<span style="color: #666666; font-family: arial, helvetica, clean, sans-serif; font-size: 13.333333969116211px; line-height: 1.4;"><span style="font-size: 14px; line-height: 14.78125px;">Ehime University Graduate School of Medicine; <span style="color: red;"><b><a href="http://shokei-kim-mitsuyama.blogspot.com/">Shokei Kim-</a></b></span></span></span><a href="http://shokei-kim-mitsuyama.blogspot.com/" style="color: #666666; font-family: 'Trebuchet MS', Trebuchet, Verdana, sans-serif; font-size: 13.333333969116211px; line-height: 1.4;"><br /></a><span style="color: red; font-family: arial, helvetica, clean, sans-serif; font-size: 13.333333969116211px; line-height: 1.4;"><span style="font-size: 14px; line-height: 14.78125px;"><b><a href="http://shokei-kim-mitsuyama.blogspot.com/" style="color: #666666;">Mitsuyama</a><span style="color: #666666;"> </span>(</b></span></span><span style="color: red; font-family: arial, helvetica, clean, sans-serif;"><span style="font-size: 14px; line-height: 14.78125px;"><b><a href="http://kim-mitsuyama-shokei.blogspot.com/">光山勝慶</a></b></span></span><b style="color: red; font-family: arial, helvetica, clean, sans-serif; font-size: 14px; line-height: 14.78125px;">), Department of Pharmacology and Molecular Therapeutics,</b><br />
<div style="color: #666666; font-family: 'Trebuchet MS', Trebuchet, Verdana, sans-serif; font-size: 13.333333969116211px; line-height: 1.4;">
<span style="font-family: arial, helvetica, clean, sans-serif;"><span style="font-size: 14px; line-height: 14.78125px;"><span style="color: red;"><b>Kumamoto University School of Medicine</b></span>; Toshihiro</span></span></div>
<div style="color: #666666; font-family: 'Trebuchet MS', Trebuchet, Verdana, sans-serif; font-size: 13.333333969116211px; line-height: 1.4;">
<span style="font-family: arial, helvetica, clean, sans-serif;"><span style="font-size: 14px; line-height: 14.78125px;">Ichiki, Department of Cardiovascular Medicine, Kyushu University</span></span></div>
<div style="color: #666666; font-family: 'Trebuchet MS', Trebuchet, Verdana, sans-serif; font-size: 13.333333969116211px; line-height: 1.4;">
<span style="font-family: arial, helvetica, clean, sans-serif;"><span style="font-size: 14px; line-height: 14.78125px;">School of Medicine, Japan.</span></span></div>
</div>
<div style="color: #666666;">
<span style="font-family: arial, helvetica, clean, sans-serif;"><span style="font-size: 14.44444465637207px; line-height: 14.774306297302246px;"><br /></span></span></div>
<div>
<hr style="color: #666666; font-family: arial, helvetica, clean, sans-serif; font-size: 0.8465em; line-height: 14.548611640930176px;" />
<div style="color: #666666;">
<br style="font-family: 'Trebuchet MS', Trebuchet, Verdana, sans-serif; font-size: 13.333333969116211px; line-height: 20px;" /></div>
<div class="cit" style="color: #666666; font-family: arial, helvetica, clean, sans-serif; font-size: 0.8465em; line-height: 1.45em;">
<span role="menubar">J Hum Hypertens.</span> 2009 Mar;23(3):188-95. doi: 10.1038/jhh.2008.116. Epub 2008 Sep 18.</div>
<h1 style="color: #666666; font-family: arial, helvetica, clean, sans-serif; font-size: 1.231em; line-height: 1.125em; margin: 0.375em 0px; position: relative;">
<span class="highlight">Rationale</span> and <span class="highlight">design</span> of the <span class="highlight">KYOTO</span> <span class="highlight">HEART</span> <span class="highlight">study</span>: <span class="highlight">effects</span> of <span class="highlight">valsartan</span> on <span class="highlight">morbidity</span> and <span class="highlight">mortality</span> in <span class="highlight">uncontrolled</span><span class="highlight">hypertensive</span> <span class="highlight">patients</span> with <span class="highlight">high</span> <span class="highlight">risk</span> of <span class="highlight">cardiovascular</span> <span class="highlight">events</span>.</h1>
<div class="auths" style="color: #666666; font-family: 'Trebuchet MS', Trebuchet, Verdana, sans-serif; font-size: 13.333333969116211px; line-height: 20px;">
<span style="font-family: arial, helvetica, clean, sans-serif;"><span style="font-size: 12.222222328186035px; line-height: 14.774306297302246px;">Sawada T, Takahashi T, Yamada H, Dahlöf B, Matsubara H; KYOTO HEART Study Group.</span></span></div>
<div style="color: #666666;">
<br style="font-family: 'Trebuchet MS', Trebuchet, Verdana, sans-serif; font-size: 13.333333969116211px; line-height: 20px;" /></div>
<div style="color: #666666;">
<span style="font-family: arial, helvetica, clean, sans-serif; font-size: xx-small;"><span style="line-height: 14.774306297302246px;"><b>Collaborators (56)</b></span></span></div>
<span style="color: #666666; font-family: arial, helvetica, clean, sans-serif; font-size: xx-small;"><span style="line-height: 18.88888931274414px;">Matsubara H </span></span><span style="color: #666666; font-family: arial, helvetica, clean, sans-serif; font-size: xx-small;"><span style="line-height: 18.875px;">(<a href="http://www.blogger.com/"><span id="goog_1934676282"></span>松原弘明<span id="goog_1934676283"></span></a>)</span></span><span style="color: #666666; font-family: arial, helvetica, clean, sans-serif; font-size: xx-small;"><span style="line-height: 18.88888931274414px;">, Dahlöf B, Sawada T, Shirayama T, Mori Y, Okigaki M, Matsumuro A, Yamada H, Tsutsumi Y, Matoba M, Takahashi T,Shiraishi H, Ikeda K, Nakamura T, Yamada T, Hirano S, Azuma A, Kimura S, Sasaki S, Shiga K, Maki K, Furukawa K, Okuda S, Kajita Y,Nishio M, Kohno Y, Kitamura M, Nishida K, Yamahara Y, Nakamura T, Sawada S, Sakai R, Kuriyama T, Miyanaga H, Kitani T, Haruyama H, Nishio A, Kinoshita N, Inagaki S, Sugihara H, Katamura M, Hachiya T, Kato S, Ohtsuki K, Higaki J, <b><a href="http://shokei-kim-mitsuyama.blogspot.com/">Kim-Mitsuyama S</a> </b></span></span><span style="color: #0000ee; font-family: arial, helvetica, clean, sans-serif; font-size: xx-small;"><span style="line-height: 18.875px;"><b><u>(<a href="http://kim-mitsuyama-shokei.blogspot.com/">光山勝慶</a>)</u></b></span></span><span style="color: #666666; font-family: arial, helvetica, clean, sans-serif; font-size: xx-small;"><span style="line-height: 18.88888931274414px;">, Ichiki T, Kitakaze M, Sugiura T, Rakugi H, Yagi K, Kanda K, Sakakura C, <span style="color: red;"><a href="http://diovan-novartis.blogspot.com/2013/05/blog-post_13.html"><b>Shirahasi N</b></a> (</span></span></span><span style="color: red; font-family: arial, helvetica, clean, sans-serif; font-size: xx-small;"><span style="line-height: 18.875px;"><a href="http://diovan-novartis.blogspot.com/2013/05/blog-post_13.html">白橋伸雄</a>)</span></span><span style="color: #666666; font-family: arial, helvetica, clean, sans-serif; font-size: xx-small; line-height: 18.88888931274414px;">, Miki M, Toyoda S.</span><br />
<div class="aff">
<h3 class="label" style="color: #724128; font-family: arial, helvetica, clean, sans-serif; font-size: 1.0769em; height: 1px; left: -10000px; line-height: 1.2857; margin: 1.2856em 0px 0.6428em; overflow: hidden; position: absolute; top: auto; width: 1px;">
Source</h3>
<div style="color: #666666; font-family: arial, helvetica, clean, sans-serif; font-size: 0.8465em; line-height: 1.0915em; margin-bottom: 0.5em; margin-top: 0.5em;">
Department of <span class="highlight">Cardiovascular</span> Medicine, <span class="highlight">Kyoto</span> Prefectural University School of Medicine, <span class="highlight">Kyoto</span>, Japan. tsawada@koto.kpu-m.ac.jp<br />
<br /></div>
<div style="color: #666666; font-family: arial, helvetica, clean, sans-serif; font-size: 0.8465em; line-height: 1.0915em; margin-bottom: 0.5em; margin-top: 0.5em;">
<span style="color: red; line-height: 20px;"><b><span style="line-height: 14.774306297302246px;">論文の本文中に、ノバルティスファーマ社員の</span><a href="http://diovan-novartis.blogspot.com/2013/05/blog-post_13.html" style="color: #bb2188; line-height: 14.774306297302246px; text-decoration: none;">白橋伸雄</a><span style="line-height: 14.774306297302246px;">氏がStatistics analysis organisationとして統計解析に関与していたことが記載されている。しかし、所属は大阪市立大学となっており、ノバルティスファーマ社員であることが隠蔽されている。</span></b></span><br />
<div>
<span style="color: red; line-height: 20px;"><b><span style="line-height: 14.774306297302246px;"><br /></span></b></span></div>
</div>
<div style="margin-bottom: 0.5em; margin-top: 0.5em;">
<div style="color: #666666; font-family: 'Trebuchet MS', Trebuchet, Verdana, sans-serif; font-size: 13.333333969116211px; line-height: 20px;">
<span style="font-family: arial, helvetica, clean, sans-serif; line-height: 14.774306297302246px;"><i><b>Statistical analysis organization</b></i></span></div>
<div style="color: #666666; font-family: 'Trebuchet MS', Trebuchet, Verdana, sans-serif; font-size: 13.333333969116211px; line-height: 20px;">
<span style="font-family: arial, helvetica, clean, sans-serif;"><span style="line-height: 14.774306297302246px;">K Yagi, Louis Pasteur Center for Medical Research,</span></span></div>
<span style="color: #666666; font-family: arial, helvetica, clean, sans-serif; font-size: 13.333333969116211px; line-height: 20px;"><span style="line-height: 14.774306297302246px;">Kyoto, Japan; <span style="color: red;"><b><a href="http://diovan-novartis.blogspot.com/2013/05/blog-post_13.html">Nobuo Shirahashi</a> (</b></span></span></span><span style="color: red; font-family: arial, helvetica, clean, sans-serif; font-size: x-small;"><span style="line-height: 14.765625px;"><b><a href="http://diovan-novartis.blogspot.com/2013/05/blog-post_13.html">白橋伸雄</a></b></span></span><span style="color: #666666; font-family: arial, helvetica, clean, sans-serif; font-size: 13.333333969116211px; line-height: 20px;"><span style="line-height: 14.774306297302246px;"><span style="color: red;"><b>)</b></span></span></span><span style="color: red; font-family: 'Trebuchet MS', Trebuchet, Verdana, sans-serif; font-size: 13.333333969116211px; line-height: 20px;"><b><span style="font-family: arial, helvetica, clean, sans-serif; line-height: 14.774306297302246px;">, Department of</span></b></span><br />
<div style="color: #666666; font-family: 'Trebuchet MS', Trebuchet, Verdana, sans-serif; font-size: 13.333333969116211px; line-height: 20px;">
<span style="color: red; font-family: arial, helvetica, clean, sans-serif;"><span style="line-height: 14.774306297302246px;"><b>Preventive Medicine and Environmental Health,</b></span></span></div>
<div style="color: #666666; font-family: 'Trebuchet MS', Trebuchet, Verdana, sans-serif; font-size: 13.333333969116211px; line-height: 20px;">
<span style="color: red; font-family: arial, helvetica, clean, sans-serif;"><span style="line-height: 14.774306297302246px;"><b>Osaka City University Medical School, Osaka,</b></span></span></div>
<div style="color: #666666; font-family: 'Trebuchet MS', Trebuchet, Verdana, sans-serif; font-size: 13.333333969116211px; line-height: 20px;">
<span style="color: red; font-family: arial, helvetica, clean, sans-serif;"><span style="line-height: 14.774306297302246px;"><b>Japan.</b></span></span></div>
</div>
</div>
<div style="color: #666666;">
<br /></div>
</div>
</div>
</div>
</div>
<hr style="background-color: white; color: #666666; font-family: arial, helvetica, clean, sans-serif; font-size: 0.8465em; line-height: 14.548611640930176px;" />
<br />
<h2 id="research_h2" style="background-color: white; border-bottom-color: rgb(170, 170, 170); border-bottom-style: dotted; border-bottom-width: 1px; color: #380038; font-family: Verdana, Arial, Helvetica, sans-serif; font-size: 14px; margin: 0px 0px 0.8em; padding: 0.5em;">
<a href="http://www.medphas.kumamoto-u.ac.jp/en/faculty/departments/27.html" style="font-size: 14px;">Department of Pharmacology and Molecular Therapeutics</a></h2>
<table id="department" style="border-collapse: collapse; border-spacing: 0px; border: 1px solid rgb(27, 63, 153); color: #222222; font-size: small; margin: 0px auto; width: 580px;"><tbody>
<tr><th style="background-color: #5f7db9; border-color: rgb(27, 63, 153); border-style: solid; border-width: 0px 0px 1px 1px; color: white; font-weight: normal; line-height: 15px; margin: 0px; padding: 5px; text-align: center; width: 150px;">Division</th><td style="background-color: #dde2f0; border-color: rgb(27, 63, 153); border-style: solid; border-width: 0px 0px 1px 1px; margin: 0px; padding: 5px; width: 430px;">Integrated Medical and Pharmaceutical Sciences</td></tr>
<tr><th style="background-color: #5f7db9; border-color: rgb(27, 63, 153); border-style: solid; border-width: 0px 0px 1px 1px; color: white; font-weight: normal; line-height: 15px; margin: 0px; padding: 5px; text-align: center; width: 150px;">Great Department</th><td style="background-color: #dde2f0; border-color: rgb(27, 63, 153); border-style: solid; border-width: 0px 0px 1px 1px; margin: 0px; padding: 5px; width: 430px;">Pharmacotherapeutics</td></tr>
<tr><th style="background-color: #5f7db9; border-color: rgb(27, 63, 153); border-style: solid; border-width: 0px 0px 1px 1px; color: white; font-weight: normal; line-height: 15px; margin: 0px; padding: 5px; text-align: center; width: 150px;">Website</th><td style="background-color: #dde2f0; border-color: rgb(27, 63, 153); border-style: solid; border-width: 0px 0px 1px 1px; margin: 0px; padding: 5px; width: 430px;"><a href="http://www.yggcsp.com/Pharmacology/" style="color: #666666; text-decoration: none;" target="_blank">http://www.yggcsp.com/Pharmacology/</a><a href="http://dcci.pharm.kumamoto-u.ac.jp/" style="color: #666666; text-decoration: none;" target="_blank"></a></td></tr>
<tr><td class="cols" colspan="2" style="background-color: #49618f; background-position: initial initial; background-repeat: initial initial; border-color: rgb(27, 63, 153); border-style: solid; border-width: 0px 0px 1px 1px; color: white; margin: 0px; padding: 5px; text-indent: 1em; width: 430px;">Staff</td></tr>
<tr><th style="background-color: #5f7db9; border-color: rgb(27, 63, 153); border-style: solid; border-width: 0px 0px 1px 1px; color: white; font-weight: normal; line-height: 15px; margin: 0px; padding: 5px; text-align: center; width: 150px;">Professor</th><td style="background-color: #dde2f0; border-color: rgb(27, 63, 153); border-style: solid; border-width: 0px 0px 1px 1px; margin: 0px; padding: 5px; width: 430px;">Shokei Mitsuyama<br />
kimmitsu(at mark)gpo.kumamoto-u.ac.jp</td></tr>
</tbody></table>
<br />
<hr style="background-color: white; color: #666666; font-family: arial, helvetica, clean, sans-serif; font-size: 0.8465em; line-height: 14.548611640930176px;" />
<br />11jigenhttp://www.blogger.com/profile/03513633746083109180noreply@blogger.com0tag:blogger.com,1999:blog-2022612537151365301.post-8073294600463395342013-05-18T22:35:00.002+09:002013-05-18T23:25:35.754+09:00経歴<br />
<br />
<div class="MsoNormal" style="margin-bottom: 0.0001pt;">
<span style="color: red;"><b><span lang="JA" style="color: red; font-family: "MS PGothic","sans-serif"; font-size: x-large; mso-bidi-font-family: "Times New Roman";">・ 光山勝慶教授の経歴</span></b><span style="font-family: 'MS PGothic', sans-serif; font-size: 13.5pt;"><o:p></o:p></span></span></div>
<div class="MsoNormal" style="margin-bottom: 0.0001pt;">
<b><span style="font-family: 'MS PGothic', sans-serif; font-size: 24pt;"><br />
<span lang="JA">氏名: 光山勝慶</span></span></b><b><span style="font-family: 'MS PGothic', sans-serif; font-size: 36pt;"> </span></b><b><u><span style="color: #0000ee; font-family: "MS PGothic","sans-serif"; font-size: 24.0pt; mso-bidi-font-family: "Times New Roman";"><span style="color: blue;"><a href="http://shokei%20kim-mitsuyama/">Shokei
Kim-Mitsuyama</a></span></span></u></b><br />
<b><span lang="JA" style="background: #B6D7A8; color: #333333; font-family: "MS PGothic","sans-serif"; font-size: 26.0pt;"><br /></span></b>
<b><span lang="JA" style="background: #B6D7A8; color: #333333; font-family: "MS PGothic","sans-serif"; font-size: 26.0pt;">学歴・職歴</span></b></div>
<table border="0" cellpadding="0" cellspacing="0" class="MsoNormalTable" style="background: white; mso-cellspacing: 0in; mso-padding-alt: 0in 0in 0in 0in; mso-yfti-tbllook: 1184; width: 540px;"><tbody>
<tr><td style="padding: 0in 0in 0in 0in; width: 405.0pt;" valign="top" width="540"><div align="right">
<table border="0" cellpadding="0" cellspacing="0" class="MsoNormalTable" style="mso-cellspacing: 0in; mso-padding-alt: 0in 0in 0in 0in; mso-yfti-tbllook: 1184; width: 500px;">
<tbody>
<tr>
<td nowrap="" style="padding: 0in 0in 0in 0in; width: 75.0pt;" valign="top" width="100"><div class="MsoNormal" style="line-height: 13.0pt; margin-bottom: .0001pt; margin-bottom: 0in;">
<span lang="JA" style="font-family: "MS Mincho"; font-size: 10.0pt; mso-bidi-font-family: "MS Mincho";">昭和</span><span style="font-family: "Times New Roman","serif"; font-size: 10.0pt; mso-fareast-font-family: "Times New Roman";">57</span><span lang="JA" style="font-family: "MS Mincho"; font-size: 10.0pt; mso-bidi-font-family: "MS Mincho";">年</span><span style="font-family: "Times New Roman","serif"; font-size: 10.0pt; mso-fareast-font-family: "Times New Roman";">3</span><span lang="JA" style="font-family: "MS Mincho"; font-size: 10.0pt; mso-bidi-font-family: "MS Mincho";">月</span><span style="font-family: "Times New Roman","serif"; font-size: 10.0pt; mso-fareast-font-family: "Times New Roman";"> <o:p></o:p></span></div>
</td>
<td style="padding: 0in 0in 0in 0in; width: 300.0pt;" valign="top" width="400"><div class="MsoNormal" style="line-height: 13.0pt; margin-bottom: .0001pt; margin-bottom: 0in;">
<span lang="JA" style="font-family: "MS Mincho"; font-size: 10.0pt; mso-bidi-font-family: "MS Mincho";">大阪市立大学医学部卒業</span><span style="font-family: "Times New Roman","serif"; font-size: 10.0pt; mso-fareast-font-family: "Times New Roman";"><o:p></o:p></span></div>
</td>
</tr>
<tr>
<td nowrap="" style="padding: 0in 0in 0in 0in; width: 75.0pt;" valign="top" width="100"><div class="MsoNormal" style="line-height: 13.0pt; margin-bottom: .0001pt; margin-bottom: 0in;">
<span lang="JA" style="font-family: "MS Mincho"; font-size: 10.0pt; mso-bidi-font-family: "MS Mincho";">昭和</span><span style="font-family: "Times New Roman","serif"; font-size: 10.0pt; mso-fareast-font-family: "Times New Roman";">57</span><span lang="JA" style="font-family: "MS Mincho"; font-size: 10.0pt; mso-bidi-font-family: "MS Mincho";">年</span><span style="font-family: "Times New Roman","serif"; font-size: 10.0pt; mso-fareast-font-family: "Times New Roman";">6</span><span lang="JA" style="font-family: "MS Mincho"; font-size: 10.0pt; mso-bidi-font-family: "MS Mincho";">月</span><span style="font-family: "Times New Roman","serif"; font-size: 10.0pt; mso-fareast-font-family: "Times New Roman";"> <o:p></o:p></span></div>
</td>
<td style="padding: 0in 0in 0in 0in; width: 300.0pt;" valign="top" width="400"><div class="MsoNormal" style="line-height: 13.0pt; margin-bottom: .0001pt; margin-bottom: 0in;">
<span lang="JA" style="font-family: "MS Mincho"; font-size: 10.0pt; mso-bidi-font-family: "MS Mincho";">大阪市立大学付属病院第一内科研修医</span><span style="font-family: "Times New Roman","serif"; font-size: 10.0pt; mso-fareast-font-family: "Times New Roman";"><o:p></o:p></span></div>
</td>
</tr>
<tr>
<td nowrap="" style="padding: 0in 0in 0in 0in; width: 75.0pt;" valign="top" width="100"><div class="MsoNormal" style="line-height: 13.0pt; margin-bottom: .0001pt; margin-bottom: 0in;">
<span lang="JA" style="font-family: "MS Mincho"; font-size: 10.0pt; mso-bidi-font-family: "MS Mincho";">昭和</span><span style="font-family: "Times New Roman","serif"; font-size: 10.0pt; mso-fareast-font-family: "Times New Roman";">62</span><span lang="JA" style="font-family: "MS Mincho"; font-size: 10.0pt; mso-bidi-font-family: "MS Mincho";">年</span><span style="font-family: "Times New Roman","serif"; font-size: 10.0pt; mso-fareast-font-family: "Times New Roman";">3</span><span lang="JA" style="font-family: "MS Mincho"; font-size: 10.0pt; mso-bidi-font-family: "MS Mincho";">月</span><span style="font-family: "Times New Roman","serif"; font-size: 10.0pt; mso-fareast-font-family: "Times New Roman";"> <o:p></o:p></span></div>
</td>
<td style="padding: 0in 0in 0in 0in; width: 300.0pt;" valign="top" width="400"><div class="MsoNormal" style="line-height: 13.0pt; margin-bottom: .0001pt; margin-bottom: 0in;">
<span lang="JA" style="font-family: "MS Mincho"; font-size: 10.0pt; mso-bidi-font-family: "MS Mincho";">大阪市立大学大学院医学研究科博士課程卒業(薬理学専攻)</span><span style="font-family: "Times New Roman","serif"; font-size: 10.0pt; mso-fareast-font-family: "Times New Roman";"><o:p></o:p></span></div>
</td>
</tr>
<tr>
<td nowrap="" style="padding: 0in 0in 0in 0in; width: 75.0pt;" valign="top" width="100"><div class="MsoNormal" style="line-height: 13.0pt; margin-bottom: .0001pt; margin-bottom: 0in;">
<span lang="JA" style="font-family: "MS Mincho"; font-size: 10.0pt; mso-bidi-font-family: "MS Mincho";">昭和</span><span style="font-family: "Times New Roman","serif"; font-size: 10.0pt; mso-fareast-font-family: "Times New Roman";">62</span><span lang="JA" style="font-family: "MS Mincho"; font-size: 10.0pt; mso-bidi-font-family: "MS Mincho";">年</span><span style="font-family: "Times New Roman","serif"; font-size: 10.0pt; mso-fareast-font-family: "Times New Roman";">4</span><span lang="JA" style="font-family: "MS Mincho"; font-size: 10.0pt; mso-bidi-font-family: "MS Mincho";">月</span><span style="font-family: "Times New Roman","serif"; font-size: 10.0pt; mso-fareast-font-family: "Times New Roman";"> <o:p></o:p></span></div>
</td>
<td style="padding: 0in 0in 0in 0in; width: 300.0pt;" valign="top" width="400"><div class="MsoNormal" style="line-height: 13.0pt; margin-bottom: .0001pt; margin-bottom: 0in;">
<span lang="JA" style="font-family: "MS Mincho"; font-size: 10.0pt; mso-bidi-font-family: "MS Mincho";">大阪市立大学医学部薬理学・助手</span><span style="font-family: "Times New Roman","serif"; font-size: 10.0pt; mso-fareast-font-family: "Times New Roman";"><o:p></o:p></span></div>
</td>
</tr>
<tr>
<td nowrap="" style="padding: 0in 0in 0in 0in; width: 75.0pt;" valign="top" width="100"><div class="MsoNormal" style="line-height: 13.0pt; margin-bottom: .0001pt; margin-bottom: 0in;">
<span lang="JA" style="font-family: "MS Mincho"; font-size: 10.0pt; mso-bidi-font-family: "MS Mincho";">平成</span><span style="font-family: "Times New Roman","serif"; font-size: 10.0pt; mso-fareast-font-family: "Times New Roman";">8</span><span lang="JA" style="font-family: "MS Mincho"; font-size: 10.0pt; mso-bidi-font-family: "MS Mincho";">年</span><span style="font-family: "Times New Roman","serif"; font-size: 10.0pt; mso-fareast-font-family: "Times New Roman";">7</span><span lang="JA" style="font-family: "MS Mincho"; font-size: 10.0pt; mso-bidi-font-family: "MS Mincho";">月</span><span style="font-family: "Times New Roman","serif"; font-size: 10.0pt; mso-fareast-font-family: "Times New Roman";"> <o:p></o:p></span></div>
</td>
<td style="padding: 0in 0in 0in 0in; width: 300.0pt;" valign="top" width="400"><div class="MsoNormal" style="line-height: 13.0pt; margin-bottom: .0001pt; margin-bottom: 0in;">
<span lang="JA" style="font-family: "MS Mincho"; font-size: 10.0pt; mso-bidi-font-family: "MS Mincho";">大阪大阪市立大学医学部薬理学・講師</span><span style="font-family: "Times New Roman","serif"; font-size: 10.0pt; mso-fareast-font-family: "Times New Roman";"><o:p></o:p></span></div>
</td>
</tr>
<tr>
<td colspan="2" style="padding: 0in 0in 0in 0in; width: 375.0pt;" valign="top" width="500"><div class="MsoNormal" style="line-height: 13.0pt; margin-bottom: .0001pt; margin-bottom: 0in;">
<span lang="JA" style="font-family: "MS Mincho"; font-size: 10.0pt; mso-bidi-font-family: "MS Mincho";">平成</span><span style="font-family: "Times New Roman","serif"; font-size: 10.0pt; mso-fareast-font-family: "Times New Roman";">9</span><span lang="JA" style="font-family: "MS Mincho"; font-size: 10.0pt; mso-bidi-font-family: "MS Mincho";">年</span><span style="font-family: "Times New Roman","serif"; font-size: 10.0pt; mso-fareast-font-family: "Times New Roman";">8</span><span lang="JA" style="font-family: "MS Mincho"; font-size: 10.0pt; mso-bidi-font-family: "MS Mincho";">月~平成</span><span style="font-family: "Times New Roman","serif"; font-size: 10.0pt; mso-fareast-font-family: "Times New Roman";">11</span><span lang="JA" style="font-family: "MS Mincho"; font-size: 10.0pt; mso-bidi-font-family: "MS Mincho";">年</span><span style="font-family: "Times New Roman","serif"; font-size: 10.0pt; mso-fareast-font-family: "Times New Roman";">3</span><span lang="JA" style="font-family: "MS Mincho"; font-size: 10.0pt; mso-bidi-font-family: "MS Mincho";">月</span><span style="font-family: "Times New Roman","serif"; font-size: 10.0pt; mso-fareast-font-family: "Times New Roman";"> <o:p></o:p></span></div>
</td>
</tr>
<tr>
<td nowrap="" style="padding: 0in 0in 0in 0in; width: 75.0pt;" valign="top" width="100"><div class="MsoNormal" style="line-height: 13.0pt; margin-bottom: .0001pt; margin-bottom: 0in;">
<span style="font-family: "Times New Roman","serif"; font-size: 10.0pt; mso-fareast-font-family: "Times New Roman";"> <o:p></o:p></span></div>
</td>
<td style="padding: 0in 0in 0in 0in; width: 300.0pt;" valign="top" width="400"><div class="MsoNormal" style="line-height: 13.0pt; margin-bottom: .0001pt; margin-bottom: 0in;">
<span lang="JA" style="font-family: "MS Mincho"; font-size: 10.0pt; mso-bidi-font-family: "MS Mincho";">筑波大学先端学際領域研究センター・客員助教授兼任</span><span style="font-family: "Times New Roman","serif"; font-size: 10.0pt; mso-fareast-font-family: "Times New Roman";"><o:p></o:p></span></div>
</td>
</tr>
<tr>
<td nowrap="" style="padding: 0in 0in 0in 0in; width: 75.0pt;" valign="top" width="100"><div class="MsoNormal" style="line-height: 13.0pt; margin-bottom: .0001pt; margin-bottom: 0in;">
<span lang="JA" style="font-family: "MS Mincho"; font-size: 10.0pt; mso-bidi-font-family: "MS Mincho";">平成</span><span style="font-family: "Times New Roman","serif"; font-size: 10.0pt; mso-fareast-font-family: "Times New Roman";">12</span><span lang="JA" style="font-family: "MS Mincho"; font-size: 10.0pt; mso-bidi-font-family: "MS Mincho";">年</span><span style="font-family: "Times New Roman","serif"; font-size: 10.0pt; mso-fareast-font-family: "Times New Roman";">6</span><span lang="JA" style="font-family: "MS Mincho"; font-size: 10.0pt; mso-bidi-font-family: "MS Mincho";">月</span><span style="font-family: "Times New Roman","serif"; font-size: 10.0pt; mso-fareast-font-family: "Times New Roman";"> <o:p></o:p></span></div>
</td>
<td style="padding: 0in 0in 0in 0in; width: 300.0pt;" valign="top" width="400"><div class="MsoNormal" style="line-height: 13.0pt; margin-bottom: .0001pt; margin-bottom: 0in;">
<span lang="JA" style="font-family: "MS Mincho"; font-size: 10.0pt; mso-bidi-font-family: "MS Mincho";">大阪市立大学大学院医学研究科分子病態薬理学・講師</span><span style="font-family: "Times New Roman","serif"; font-size: 10.0pt; mso-fareast-font-family: "Times New Roman";"><o:p></o:p></span></div>
</td>
</tr>
<tr>
<td nowrap="" style="padding: 0in 0in 0in 0in; width: 75.0pt;" valign="top" width="100"><div class="MsoNormal" style="line-height: 13.0pt; margin-bottom: .0001pt; margin-bottom: 0in;">
<span lang="JA" style="font-family: "MS Mincho"; font-size: 10.0pt; mso-bidi-font-family: "MS Mincho";">平成</span><span style="font-family: "Times New Roman","serif"; font-size: 10.0pt; mso-fareast-font-family: "Times New Roman";">13</span><span lang="JA" style="font-family: "MS Mincho"; font-size: 10.0pt; mso-bidi-font-family: "MS Mincho";">年</span><span style="font-family: "Times New Roman","serif"; font-size: 10.0pt; mso-fareast-font-family: "Times New Roman";">10</span><span lang="JA" style="font-family: "MS Mincho"; font-size: 10.0pt; mso-bidi-font-family: "MS Mincho";">月</span><span style="font-family: "Times New Roman","serif"; font-size: 10.0pt; mso-fareast-font-family: "Times New Roman";"> <o:p></o:p></span></div>
</td>
<td style="padding: 0in 0in 0in 0in; width: 300.0pt;" valign="top" width="400"><div class="MsoNormal" style="line-height: 13.0pt; margin-bottom: .0001pt; margin-bottom: 0in;">
<span lang="JA" style="font-family: "MS Mincho"; font-size: 10.0pt; mso-bidi-font-family: "MS Mincho";">大阪市立大学大学院医学研究科分子病態薬理学・助教授</span><span style="font-family: "Times New Roman","serif"; font-size: 10.0pt; mso-fareast-font-family: "Times New Roman";"><o:p></o:p></span></div>
</td>
</tr>
<tr>
<td colspan="2" style="padding: 0in 0in 0in 0in; width: 375.0pt;" valign="top" width="500"><div class="MsoNormal" style="line-height: 13.0pt; margin-bottom: .0001pt; margin-bottom: 0in;">
<span lang="JA" style="font-family: "MS Mincho"; font-size: 10.0pt; mso-bidi-font-family: "MS Mincho";">平成</span><span style="font-family: "Times New Roman","serif"; font-size: 10.0pt; mso-fareast-font-family: "Times New Roman";">16</span><span lang="JA" style="font-family: "MS Mincho"; font-size: 10.0pt; mso-bidi-font-family: "MS Mincho";">年</span><span style="font-family: "Times New Roman","serif"; font-size: 10.0pt; mso-fareast-font-family: "Times New Roman";">2</span><span lang="JA" style="font-family: "MS Mincho"; font-size: 10.0pt; mso-bidi-font-family: "MS Mincho";">月</span><span style="font-family: "Times New Roman","serif"; font-size: 10.0pt; mso-fareast-font-family: "Times New Roman";">1</span><span lang="JA" style="font-family: "MS Mincho"; font-size: 10.0pt; mso-bidi-font-family: "MS Mincho";">日</span><span style="font-family: "Times New Roman","serif"; font-size: 10.0pt; mso-fareast-font-family: "Times New Roman";"> <o:p></o:p></span></div>
</td>
</tr>
<tr>
<td nowrap="" style="padding: 0in 0in 0in 0in; width: 75.0pt;" valign="top" width="100"><div class="MsoNormal" style="line-height: 13.0pt; margin-bottom: .0001pt; margin-bottom: 0in;">
<span style="font-family: "Times New Roman","serif"; font-size: 10.0pt; mso-fareast-font-family: "Times New Roman";"> <o:p></o:p></span></div>
</td>
<td style="padding: 0in 0in 0in 0in; width: 300.0pt;" valign="top" width="400"><div class="MsoNormal" style="line-height: 13.0pt; margin-bottom: .0001pt; margin-bottom: 0in;">
<span lang="JA" style="font-family: "MS Mincho"; font-size: 10.0pt; mso-bidi-font-family: "MS Mincho";">熊本大学大学院生命科学研究部生体機能薬理学</span><span style="font-family: "Times New Roman","serif"; font-size: 10.0pt; mso-fareast-font-family: "Times New Roman";"><br />
</span><span lang="JA" style="font-family: "MS Mincho"; font-size: 10.0pt; mso-bidi-font-family: "MS Mincho";">(医学部薬理学第二)教授</span><span style="font-family: "Times New Roman","serif"; font-size: 10.0pt; mso-fareast-font-family: "Times New Roman";"><o:p></o:p></span></div>
</td>
</tr>
<tr>
<td colspan="2" style="padding: 0in 0in 0in 0in; width: 375.0pt;" valign="top" width="500"><div class="MsoNormal" style="line-height: 13.0pt; margin-bottom: .0001pt; margin-bottom: 0in;">
<span lang="JA" style="font-family: "MS Mincho"; font-size: 10.0pt; mso-bidi-font-family: "MS Mincho";">平成</span><span style="font-family: "Times New Roman","serif"; font-size: 10.0pt; mso-fareast-font-family: "Times New Roman";">22</span><span lang="JA" style="font-family: "MS Mincho"; font-size: 10.0pt; mso-bidi-font-family: "MS Mincho";">年</span><span style="font-family: "Times New Roman","serif"; font-size: 10.0pt; mso-fareast-font-family: "Times New Roman";">1</span><span lang="JA" style="font-family: "MS Mincho"; font-size: 10.0pt; mso-bidi-font-family: "MS Mincho";">月</span><span style="font-family: "Times New Roman","serif"; font-size: 10.0pt; mso-fareast-font-family: "Times New Roman";">1</span><span lang="JA" style="font-family: "MS Mincho"; font-size: 10.0pt; mso-bidi-font-family: "MS Mincho";">日~現在</span><span style="font-family: "Times New Roman","serif"; font-size: 10.0pt; mso-fareast-font-family: "Times New Roman";"> <o:p></o:p></span></div>
</td>
</tr>
<tr>
<td nowrap="" style="padding: 0in 0in 0in 0in; width: 75.0pt;" valign="top" width="100"><div class="MsoNormal" style="line-height: 13.0pt; margin-bottom: .0001pt; margin-bottom: 0in;">
<span style="font-family: "Times New Roman","serif"; font-size: 10.0pt; mso-fareast-font-family: "Times New Roman";"> <o:p></o:p></span></div>
</td>
<td style="padding: 0in 0in 0in 0in; width: 300.0pt;" valign="top" width="400"><div class="MsoNormal" style="line-height: 13.0pt; margin-bottom: .0001pt; margin-bottom: 0in;">
<span lang="JA" style="font-family: "MS Mincho"; font-size: 10.0pt; mso-bidi-font-family: "MS Mincho";">熊本大学大学院生命科学研究部医学系生体機能薬理学</span><span style="font-family: "Times New Roman","serif"; font-size: 10.0pt; mso-fareast-font-family: "Times New Roman";"><br />
</span><span lang="JA" style="font-family: "MS Mincho"; font-size: 10.0pt; mso-bidi-font-family: "MS Mincho";">(医学部薬理学第二)教授</span><span style="font-family: "Times New Roman","serif"; font-size: 10.0pt; mso-fareast-font-family: "Times New Roman";"><o:p></o:p></span></div>
</td>
</tr>
</tbody></table>
</div>
</td>
</tr>
</tbody></table>
<div class="MsoNormal" style="margin-bottom: 0.0001pt;">
<table border="0" cellpadding="0" cellspacing="3" class="MsoNormalTable" style="background: white; mso-cellspacing: 2.2pt; mso-padding-alt: 0in 0in 0in 0in; mso-yfti-tbllook: 1184; width: 560px;"><tbody>
<tr><td style="padding: 0in 0in 0in 0in; width: 415.5pt;" width="554"><div class="MsoNormal" style="line-height: 15.0pt; margin-bottom: .0001pt; margin-bottom: 0in;">
<b><span lang="JA" style="font-family: "MS Mincho"; font-size: 10.0pt; mso-bidi-font-family: "MS Mincho";">兼任</span></b><b><span style="font-family: "MS Mincho"; font-size: 10.0pt; mso-bidi-font-family: "MS Mincho";">: </span></b><span lang="JA" style="font-family: "MS Mincho"; font-size: 10.0pt; mso-bidi-font-family: "MS Mincho"; mso-bidi-font-weight: bold;">平成</span><span style="font-family: "MS Mincho"; font-size: 10.0pt; mso-bidi-font-family: "MS Mincho"; mso-bidi-font-weight: bold;">16<span lang="JA">年</span>7<span lang="JA">月</span>1<span lang="JA">日~現在 大阪市立大学大学院医学研究科・客員教授</span><o:p></o:p></span></div>
<div class="MsoNormal" style="line-height: 15.0pt; margin-bottom: .0001pt; margin-bottom: 0in;">
<br /></div>
<div class="MsoNormal" style="margin-bottom: 0.0001pt;">
<b><span style="background: #B6D7A8; color: #333333; font-family: "MS PGothic","sans-serif"; font-size: 26.0pt;"><br /></span></b>
<b><span style="background: #B6D7A8; color: #333333; font-family: "MS PGothic","sans-serif"; font-size: 26.0pt;">Kyoto Heart Study<span lang="JA">の</span>Endpoint
committee<span lang="JA">委員</span><o:p></o:p></span></b></div>
<div class="MsoNormal" style="margin-bottom: .0001pt; margin-bottom: 0in; mso-line-height-alt: 13.0pt;">
<span lang="JA" style="font-family: "MS Mincho"; font-size: 14.0pt; mso-bidi-font-family: "MS Mincho";">→ <a href="http://diovan-novartis.blogspot.com/">ノバルティス ディオバン(バルサルタン)臨床研究データ捏造疑惑</a></span><span style="font-family: "MS Mincho"; font-size: 14.0pt; mso-bidi-font-family: "MS Mincho";"><o:p></o:p></span></div>
<div class="MsoNormal" style="margin-bottom: .0001pt; margin-bottom: 0in; mso-line-height-alt: 13.0pt;">
<span lang="JA" style="font-family: "MS Mincho"; font-size: 14.0pt; mso-bidi-font-family: "MS Mincho";">→ </span><span style="font-family: "MS Mincho"; font-size: 14.0pt; mso-bidi-font-family: "MS Mincho";"><a href="http://diovan-novartis.blogspot.com/2013/05/kyoto-heart-study.html">Kyoto Heart Study</a><o:p></o:p></span></div>
<div class="MsoNormal" style="line-height: 15.0pt; margin-bottom: .0001pt; margin-bottom: 0in;">
<br /></div>
<div class="MsoNormal" style="margin-bottom: 0.0001pt;">
<b><span lang="JA" style="background: #B6D7A8; color: #333333; font-family: "MS PGothic","sans-serif"; font-size: 26.0pt;">専門分野</span></b><b><span style="background: #B6D7A8; color: #333333; font-family: "MS PGothic","sans-serif"; font-size: 26.0pt;"><o:p></o:p></span></b></div>
<div class="MsoNormal" style="line-height: 15.0pt; margin-bottom: .0001pt; margin-bottom: 0in;">
<span lang="JA" style="font-family: "MS Mincho"; font-size: 10.0pt; mso-bidi-font-family: "MS Mincho"; mso-bidi-font-weight: bold;">循環器薬理、腎臓薬理、細胞内シグナル伝達系をターゲットにした創薬、遺伝子治療、レニン・アンジオテンシン系</span><span style="font-family: "MS Mincho"; font-size: 10.0pt; mso-bidi-font-family: "MS Mincho"; mso-bidi-font-weight: bold;"><o:p></o:p></span></div>
<div class="MsoNormal" style="line-height: 15.0pt; margin-bottom: .0001pt; margin-bottom: 0in;">
<br /></div>
<div class="MsoNormal" style="line-height: 15.0pt; margin-bottom: .0001pt; margin-bottom: 0in;">
<br /></div>
<div class="MsoNormal" style="margin-bottom: 0.0001pt;">
<b><span lang="JA" style="background: #B6D7A8; color: #333333; font-family: "MS PGothic","sans-serif"; font-size: 26.0pt;">所属学会</span></b><b><span style="background: #B6D7A8; color: #333333; font-family: "MS PGothic","sans-serif"; font-size: 26.0pt;"><o:p></o:p></span></b></div>
<div class="MsoNormal" style="line-height: 15.0pt; margin-bottom: .0001pt; margin-bottom: 0in;">
<span lang="JA" style="font-family: "MS Mincho"; font-size: 10.0pt; mso-bidi-font-family: "MS Mincho"; mso-bidi-font-weight: bold;">■所属学会 日本循環器学会(理事)</span><span style="font-family: "MS Mincho"; font-size: 10.0pt; mso-bidi-font-family: "MS Mincho"; mso-bidi-font-weight: bold;"><o:p></o:p></span></div>
<div class="MsoNormal" style="line-height: 15.0pt; margin-bottom: .0001pt; margin-bottom: 0in;">
<span lang="JA" style="font-family: "MS Mincho"; font-size: 10.0pt; mso-bidi-font-family: "MS Mincho"; mso-bidi-font-weight: bold;">日本高血圧学会(理事) </span><span style="font-family: "MS Mincho"; font-size: 10.0pt; mso-bidi-font-family: "MS Mincho"; mso-bidi-font-weight: bold;"><o:p></o:p></span></div>
<div class="MsoNormal" style="line-height: 15.0pt; margin-bottom: .0001pt; margin-bottom: 0in;">
<span lang="JA" style="font-family: "MS Mincho"; font-size: 10.0pt; mso-bidi-font-family: "MS Mincho"; mso-bidi-font-weight: bold;">日本循環制御医学会(理事) </span><span style="font-family: "MS Mincho"; font-size: 10.0pt; mso-bidi-font-family: "MS Mincho"; mso-bidi-font-weight: bold;"><o:p></o:p></span></div>
<div class="MsoNormal" style="line-height: 15.0pt; margin-bottom: .0001pt; margin-bottom: 0in;">
<span style="font-family: "MS Mincho"; font-size: 10.0pt; mso-bidi-font-family: "MS Mincho"; mso-bidi-font-weight: bold;">Fellow of American Heart Association
Fellow of the European Society of Cardiology <span lang="JA">日本臨床薬理学会(評議員) </span><o:p></o:p></span></div>
<div class="MsoNormal" style="line-height: 15.0pt; margin-bottom: .0001pt; margin-bottom: 0in;">
<span lang="JA" style="font-family: "MS Mincho"; font-size: 10.0pt; mso-bidi-font-family: "MS Mincho"; mso-bidi-font-weight: bold;">日本薬理学会(評議員) </span><span style="font-family: "MS Mincho"; font-size: 10.0pt; mso-bidi-font-family: "MS Mincho"; mso-bidi-font-weight: bold;"><o:p></o:p></span></div>
<div class="MsoNormal" style="line-height: 15.0pt; margin-bottom: .0001pt; margin-bottom: 0in;">
<span lang="JA" style="font-family: "MS Mincho"; font-size: 10.0pt; mso-bidi-font-family: "MS Mincho"; mso-bidi-font-weight: bold;">日本動脈硬化学会(評議員) </span><span style="font-family: "MS Mincho"; font-size: 10.0pt; mso-bidi-font-family: "MS Mincho"; mso-bidi-font-weight: bold;"><o:p></o:p></span></div>
<div class="MsoNormal" style="line-height: 15.0pt; margin-bottom: .0001pt; margin-bottom: 0in;">
<span lang="JA" style="font-family: "MS Mincho"; font-size: 10.0pt; mso-bidi-font-family: "MS Mincho"; mso-bidi-font-weight: bold;">国際心臓研究学会日本部会(評議員)
</span><span style="font-family: "MS Mincho"; font-size: 10.0pt; mso-bidi-font-family: "MS Mincho"; mso-bidi-font-weight: bold;"><o:p></o:p></span></div>
<div class="MsoNormal" style="line-height: 15.0pt; margin-bottom: .0001pt; margin-bottom: 0in;">
<span lang="JA" style="font-family: "MS Mincho"; font-size: 10.0pt; mso-bidi-font-family: "MS Mincho"; mso-bidi-font-weight: bold;">日本心血管内分泌代謝学会(評議員)
</span><span style="font-family: "MS Mincho"; font-size: 10.0pt; mso-bidi-font-family: "MS Mincho"; mso-bidi-font-weight: bold;"><o:p></o:p></span></div>
<div class="MsoNormal" style="line-height: 15.0pt; margin-bottom: .0001pt; margin-bottom: 0in;">
<span lang="JA" style="font-family: "MS Mincho"; font-size: 10.0pt; mso-bidi-font-family: "MS Mincho"; mso-bidi-font-weight: bold;">日本抗加齢医学会(評議員) </span><span style="font-family: "MS Mincho"; font-size: 10.0pt; mso-bidi-font-family: "MS Mincho"; mso-bidi-font-weight: bold;"><o:p></o:p></span></div>
<div class="MsoNormal" style="line-height: 15.0pt; margin-bottom: .0001pt; margin-bottom: 0in;">
<span lang="JA" style="font-family: "MS Mincho"; font-size: 10.0pt; mso-bidi-font-family: "MS Mincho"; mso-bidi-font-weight: bold;">日本循環薬理学会(幹事) </span><span style="font-family: "MS Mincho"; font-size: 10.0pt; mso-bidi-font-family: "MS Mincho"; mso-bidi-font-weight: bold;"><o:p></o:p></span></div>
<div class="MsoNormal" style="line-height: 15.0pt; margin-bottom: .0001pt; margin-bottom: 0in;">
<span lang="JA" style="font-family: "MS Mincho"; font-size: 10.0pt; mso-bidi-font-family: "MS Mincho"; mso-bidi-font-weight: bold;">日本血管生物医学会(評議員) </span><span style="font-family: "MS Mincho"; font-size: 10.0pt; mso-bidi-font-family: "MS Mincho"; mso-bidi-font-weight: bold;"><o:p></o:p></span></div>
<div class="MsoNormal" style="line-height: 15.0pt; margin-bottom: .0001pt; margin-bottom: 0in;">
<span lang="JA" style="font-family: "MS Mincho"; font-size: 10.0pt; mso-bidi-font-family: "MS Mincho"; mso-bidi-font-weight: bold;">日本心脈管作動物質学会(評議員) </span><span style="font-family: "MS Mincho"; font-size: 10.0pt; mso-bidi-font-family: "MS Mincho"; mso-bidi-font-weight: bold;"><o:p></o:p></span></div>
<div class="MsoNormal" style="line-height: 15.0pt; margin-bottom: .0001pt; margin-bottom: 0in;">
<span lang="JA" style="font-family: "MS Mincho"; font-size: 10.0pt; mso-bidi-font-family: "MS Mincho"; mso-bidi-font-weight: bold;">日本腎臓学会 日本糖尿病学会など (編集委員)
</span><span style="font-family: "MS Mincho"; font-size: 10.0pt; mso-bidi-font-family: "MS Mincho"; mso-bidi-font-weight: bold;"><o:p></o:p></span></div>
<div class="MsoNormal" style="line-height: 15.0pt; margin-bottom: .0001pt; margin-bottom: 0in;">
<span style="font-family: "MS Mincho"; font-size: 10.0pt; mso-bidi-font-family: "MS Mincho"; mso-bidi-font-weight: bold;">Hypertension Research
(Editor-in-Chief) Circulation Journal (Editorial Board) <span lang="JA">など</span><o:p></o:p></span></div>
</td></tr>
</tbody></table>
</div>
<div class="MsoNormal" style="margin-bottom: 0.0001pt;">
<br /></div>
<div class="MsoNormal" style="margin-bottom: 0.0001pt;">
<br /></div>
<div class="MsoNormal" style="margin-bottom: 0.0001pt;">
<br /></div>
<table border="0" cellpadding="0" cellspacing="3" style="background-color: white;"><tbody>
<tr><td align="left" class="grtidxnm" nowrap="" style="font-size: 10pt; font-weight: bold; line-height: 15pt;" valign="top" width="100"><br /></td><td align="left" class="grtidxmsg" style="font-size: 10pt; line-height: 13pt;" valign="top" width="434"><br /></td></tr>
</tbody></table>
<br />11jigenhttp://www.blogger.com/profile/03513633746083109180noreply@blogger.com0tag:blogger.com,1999:blog-2022612537151365301.post-89332329131859252212013-05-18T22:24:00.002+09:002013-05-20T11:32:03.999+09:00疑惑論文に関連する公的研究費、競争的資金まとめ<b><span style="color: red; font-size: small;">公的研究費1</span></b><br />
<b>科学研究費(文部科学省、日本学術振興会)</b><br />
基盤研究(B)、総額:15770千円、研究代表者:(<a href="http://kaken.nii.ac.jp/d/r/00137192.ja.html">岩尾 洋</a>)<br />
研究家題名: <a href="http://kaken.nii.ac.jp/d/p/17390068">アンジオテンシン受容体シグナルクロストークのプロテオームの解析</a><br />
Proteomic amalysis in Angiotensin signaling<br />
研究課題番号: 17390068<br />
<a href="http://kaken.nii.ac.jp/d/p/17390068/2005/3/ja.ja.html">2005年度 研究実績報告書</a>と、2<a href="http://kaken.nii.ac.jp/d/p/17390068/2007/6/ja.ja.html">007年度 研究成果報告書概要</a>に、疑惑論文の<a href="http://kim-mitsuyama-shokei.blogspot.com/2013/05/beneficial-effect-of-candesartan-on-rat.html">J Pharmacol Sci. 2005 Aug;98(4):372-9.</a>と、<a href="http://kim-mitsuyama-shokei.blogspot.com/2013/05/excess-aldosterone-under-normal-salt.html">Hypertens Res. 2005 May;28(5):447-55.</a>が記載されている。<br />
<br />
<b><span style="color: red; font-size: small;">公的研究費2</span></b><br />
<b>科学研究費(文部科学省、日本学術振興会)</b><br />
基盤研究(C)、総額:3500千円、研究代表者:(<a href="http://kim-mitsuyama-shokei.blogspot.com/">光山 勝慶</a> (金 勝慶))<br />
研究家題名: <a href="http://kaken.nii.ac.jp/d/p/16590202">血管新生、血管リモデリングの細胞分子薬理学的研究と創薬への応用</a><br />
<span style="background-color: white; font-family: Tahoma, Verdana, Arial, 'ヒラギノ角ゴ Pro W3', 'MS Pゴシック', sans-serif; font-size: 14px; line-height: 16px;">Investigation on cellular and molecular mechanism of angiogenesis and vascular remodeling and their novel therapeutic target</span><br />
研究課題番号: 16590202<br />
<a href="http://kaken.nii.ac.jp/d/p/16590202/2005/3/ja.ja.html">2005年度 研究実績報告書</a>に、疑惑論文の<a href="http://kim-mitsuyama-shokei.blogspot.com/2013/05/excess-aldosterone-under-normal-salt.html">Hypertens Res. 2005 May;28(5):447-55.</a>が記載されている。<br />
<a href="http://kaken.nii.ac.jp/d/p/16590202/2005/6/ja.ja.html">2005年度 研究成果報告書概要</a>に、疑惑論文の<a href="http://kim-mitsuyama-shokei.blogspot.com/2013/05/advanced-glycation-end-products.html">Circulation. 2006 Mar 14;113(10):1353-60.</a>と、<a href="http://kim-mitsuyama-shokei.blogspot.com/2013/05/beneficial-effect-of-candesartan-on-rat.html">J Pharmacol Sci. 2005 Aug;98(4):372-9.</a>と、<a href="http://kim-mitsuyama-shokei.blogspot.com/2013/05/excess-aldosterone-under-normal-salt.html">Hypertens Res. 2005 May;28(5):447-55.</a>が記載されている。<br />
<div>
<br /></div>
<div>
<big><b><span style="color: red; font-size: small;">公的研究費3</span></b></big><br />
<b>科学研究費(文部科学省、日本学術振興会)</b><br />
基盤研究(C)、総額:3500千円、研究代表者:(秋岡 要)<br />
研究家題名: <a href="http://kaken.nii.ac.jp/d/p/14570684">遺伝子導入した培養骨格筋細胞移植による心筋梗塞治療</a><br />
<span style="font-family: Tahoma, Verdana, Arial, ヒラギノ角ゴ Pro W3, MS Pゴシック, sans-serif;"><span style="font-size: 15.0150146484375px; line-height: 15.976914405822754px;">Treatment of myocardial infarction by transplantation of gene-transferred myocyte</span></span><br />
研究課題番号: 14570684<br />
<a href="http://kaken.nii.ac.jp/d/p/14570684/2003/6/ja.ja.html">2003年度 研究成果報告書概要</a>に、疑惑論文の<a href="http://kim-mitsuyama-shokei.blogspot.com/2013/05/apoptosis-signal-regulating-kinase-1.html">Circ Res. 2003 Oct 31;93(9):874-83.</a>が記載されている。<br />
<br />
<big><b><span style="color: red; font-size: small;">公的研究費4</span></b></big><br />
<b>科学研究費(文部科学省、日本学術振興会)</b><br />
基盤研究(C)、総額:3600千円、研究代表者:(<a href="http://kim-mitsuyama-shokei.blogspot.com/">光山 勝慶</a> (金 勝慶))<br />
研究家題名: <a href="http://kaken.nii.ac.jp/d/p/14570083">心血管病の分子機構とASK1の役割に関する研究</a><br />
Role of ASK1 in Molecular Mechanism of Cardiovascular Diseases<br />
研究課題番号:14570083<br />
<a href="http://kaken.nii.ac.jp/d/p/14570083/2003/3/ja.ja.html">2003年度 研究実績報告書</a>に、疑惑論文の<a href="http://kim-mitsuyama-shokei.blogspot.com/2013/05/apoptosis-signal-regulating-kinase-1.html">Circ Res. 2003 Oct 31;93(9):874-83.</a>が記載されている。<br />
また、<a href="http://kaken.nii.ac.jp/d/p/14570083/2003/6/ja.ja.html">2003年度 研究成果報告書概要</a>に、疑惑論文の<a href="http://kim-mitsuyama-shokei.blogspot.com/2013/05/apoptosis-signal-regulating-kinase-1.html">Circ Res. 2003 Oct 31;93(9):874-83.</a>と、<a href="http://kim-mitsuyama-shokei.blogspot.com/2013/05/differential-contribution-of-three.html">J Am Soc Nephrol. 2003 Mar;14(3):584-92.</a>が記載されている。<br />
<br />
<b><span style="color: red; font-size: small;">公的研究費5</span></b><br />
<b>科学研究費(文部科学省、日本学術振興会)</b><br />
基盤研究(B)、総額:13900千円、研究代表者:(岩尾 洋)、研究分担者: (<a href="http://kim-mitsuyama-shokei.blogspot.com/">光山 勝慶</a>)<br />
研究家題名:<a href="http://kaken.nii.ac.jp/d/p/14370036"> 臓器障害におけるMAPキナーゼの役割と網羅的遺伝子発現解析</a><br />
研究課題番号: 14370036<br />
<a href="http://kaken.nii.ac.jp/d/p/14370036/2002/3/ja.ja.html">2002年度 研究実績報告書</a>に、疑惑論文の<a href="http://kim-mitsuyama-shokei.blogspot.com/2013/05/differential-contribution-of-three.html">J Am Soc Nephrol. 2003 Mar;14(3):584-92.</a>が記載されている。<br />
<a href="http://kaken.nii.ac.jp/d/p/14370036/2003/3/ja.ja.html">2003年度 研究実績報告書</a>に、疑惑論文の<a href="http://kim-mitsuyama-shokei.blogspot.com/2013/05/apoptosis-signal-regulating-kinase-1.html">Circ Res. 2003 Oct 31;93(9):874-83.</a>が記載されている。<br />
<a href="http://kaken.nii.ac.jp/d/p/14370036/2003/6/ja.ja.html">2003年度 研究成果報告書概要</a>に、疑惑論文の<a href="http://kim-mitsuyama-shokei.blogspot.com/2013/05/differential-contribution-of-three.html">J Am Soc Nephrol. 2003 Mar;14(3):584-92.</a>と、<a href="http://kim-mitsuyama-shokei.blogspot.com/2013/05/apoptosis-signal-regulating-kinase-1.html">Circ Res. 2003 Oct 31;93(9):874-83.</a>が記載されている。<br />
<br />
<b><span style="color: red; font-size: small;">公的研究費6</span></b><br />
<b>科学研究費(文部科学省、日本学術振興会)</b><br />
基盤研究(C)、総額:2700千円、研究代表者:(<a href="http://kim-mitsuyama-shokei.blogspot.com/">光山 勝慶</a> (金 勝慶))<br />
研究家題名: <a href="http://kaken.nii.ac.jp/d/p/09670101">MAPキナーゼファミリーの活性化機構と心血管障害における役割-in vivoでの検討-</a><br />
<span style="background-color: white; font-family: Tahoma, Verdana, Arial, 'ヒラギノ角ゴ Pro W3', 'MS Pゴシック', sans-serif; font-size: 14.666666984558105px; line-height: 18.66666603088379px;">Activation of MAP Kinases and role in cardiovascular diseases - in vivo study -</span><br />
研究課題番号:09670101<br />
<a href="http://kaken.nii.ac.jp/d/p/09670101/1998/3/ja.ja.html">1998年度 研究実績報告書</a>に、疑惑論文の<a href="http://kim-mitsuyama-shokei.blogspot.com/2013/05/differential-activation-of-cardiac-c.html">Circ Res. 1998 Oct 5;83(7):752-60.</a>が記載されている。<br />
また、<a href="http://kaken.nii.ac.jp/d/p/09670101/1998/6/ja.ja.html">1998年度 研究成果報告書概要</a>に、疑惑論文の<a href="http://kim-mitsuyama-shokei.blogspot.com/2013/05/differential-activation-of-cardiac-c.html">Circ Res. 1998 Oct 5;83(7):752-60.</a>と、<a href="http://kim-mitsuyama-shokei.blogspot.com/2013/05/cardiac-mitogen-activated-protein.html">Hypertension. 1998 Jan;31(1):50-6.</a>が記載されている。<br />
<br />
<b><span style="color: red; font-size: small;">公的研究費7</span></b><br />
<b>科学研究費(文部科学省、日本学術振興会)</b><br />
基盤研究(B)、総額:4700千円、研究代表者:岩尾 洋、研究分担者: (<a href="http://kim-mitsuyama-shokei.blogspot.com/">光山 勝慶</a>)<br />
研究家題名: <a href="http://kaken.nii.ac.jp/d/p/09470527">心血管障害の分子機構の解明-細胞増殖とリモテリング-</a><br />
<span style="background-color: white; font-family: Tahoma, Verdana, Arial, 'ヒラギノ角ゴ Pro W3', 'MS Pゴシック', sans-serif; font-size: 14.666666984558105px; line-height: 18.66666603088379px;">MOLECULAR MECHANISUMS OF CARDIOVASCULAR REMODELING</span><br />
研究課題番号:09470527<br />
<a href="http://kaken.nii.ac.jp/d/p/09470527/1998/3/ja.ja.html">1998年度 研究実績報告書</a>に、疑惑論文の<a href="http://kim-mitsuyama-shokei.blogspot.com/2013/05/differential-activation-of-cardiac-c.html">Circ Res. 1998 Oct 5;83(7):752-60.</a>と、<a href="http://kim-mitsuyama-shokei.blogspot.com/2013/05/cardiac-mitogen-activated-protein.html">Hypertension. 1998 Jan;31(1):50-6.</a>が記載されている。<br />
<br />
<br />
<br />
<br />
<br />
<br />
<br /></div>
11jigenhttp://www.blogger.com/profile/03513633746083109180noreply@blogger.com0tag:blogger.com,1999:blog-2022612537151365301.post-23568317233478806552013-05-18T22:23:00.002+09:002013-05-20T10:08:19.027+09:00Calcium channel blockers, more than diuretics, enhance vascular protective effects of angiotensin receptor blockers in salt-loaded hypertensive rats.<br />
<br />
<div class="cit" style="background-color: white; font-family: arial, helvetica, clean, sans-serif; font-size: 0.8465em; line-height: 1.45em;">
<span role="menubar">PLoS One.</span> 2012;7(6):e39162. doi: 10.1371/journal.pone.0039162. Epub 2012 Jun 14.</div>
<h1 style="background-color: white; font-family: arial, helvetica, clean, sans-serif; font-size: 1.231em; line-height: 1.125em; margin: 0.375em 0px;">
Calcium channel blockers, more than diuretics, enhance vascular protective effects of angiotensin receptor blockers in salt-loaded hypertensive rats.</h1>
<div class="auths" style="background-color: white;">
<span style="font-family: arial, helvetica, clean, sans-serif;"><span style="font-size: 14.666666984558105px;">Yamamoto E, Kataoka K, Dong YF, Koibuchi N, Toyama K, Sueta D, Katayama T, Yasuda O, Ogawa H, <a href="http://shokei-kim-mitsuyama.blogspot.com/">Kim-Mitsuyama S</a>.</span></span></div>
<div class="aff" style="background-color: white; line-height: 1.0915em;">
<h3 class="label" style="color: #724128; font-family: arial, helvetica, clean, sans-serif; font-size: 1.0769em; height: 1px; left: -10000px; line-height: 1.2857; margin: 1.2856em 0px 0.6428em; overflow: hidden; position: absolute; top: auto; width: 1px;">
Source</h3>
<div style="font-family: arial, helvetica, clean, sans-serif; font-size: 0.8465em; margin-bottom: 0.5em; margin-top: 0.5em;">
Department of Pharmacology and Molecular Therapeutics, Kumamoto University Graduate School of Medical Sciences, Kumamoto, Japan.</div>
<div style="font-family: arial, helvetica, clean, sans-serif; font-size: 0.8465em; margin-bottom: 0.5em; margin-top: 0.5em;">
<br /></div>
<div style="font-family: arial, helvetica, clean, sans-serif; font-size: 0.8465em; margin-bottom: 0.5em; margin-top: 0.5em;">
<a href="http://www.ncbi.nlm.nih.gov/pubmed/22720058">http://www.ncbi.nlm.nih.gov/pubmed/22720058</a></div>
<div style="font-family: arial, helvetica, clean, sans-serif; font-size: 0.8465em; margin-bottom: 0.5em; margin-top: 0.5em;">
<a href="http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0039162">http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0039162</a></div>
<div style="font-family: arial, helvetica, clean, sans-serif; font-size: 0.8465em; margin-bottom: 0.5em; margin-top: 0.5em;">
<br />
<br />
<br />
<div style="color: #666666; font-family: 'Trebuchet MS', Trebuchet, Verdana, sans-serif; font-size: 13.333333015441895px; line-height: 14.541666984558105px;">
<div style="font-size: 13.333333015441895px; line-height: 14.541666984558105px;">
<hr style="font-family: arial, helvetica, clean, sans-serif; font-size: 0.8465em; line-height: 14.541666984558105px;" />
<br /></div>
</div>
<br />
<br />
<div style="font-family: 'MS PGothic'; font-size: medium; line-height: normal;">
・ Fig.4(A)とFig.4(B)のTubulilnの左から2,3,4レーン目の画像(Ol, Az, Hy)が、Fig.4(C)のTubulinの左から1,2,3レーン目の画像(Ve, Ol, Az)に類似している。</div>
<div style="font-family: 'MS PGothic'; font-size: medium; line-height: normal;">
さらに、Fig.4(A)とFig.4(B)のTubulilnの左から5,6,7レーン目の画像(Ol+Ax, Ol+Hy, WKY)が、Fig.4(C)のTubulinの左から4,5,6レーン目の画像(Hy, Ol+Az, Ol+Hy)に類似している。</div>
<div style="font-family: 'MS PGothic'; font-size: medium; line-height: normal;">
Fig.4(A)とFig.4(B)のTubulinの左から4レーン目と5レーン目の間に編集の跡を見ることができる。</div>
<div style="font-family: 'MS PGothic'; font-size: medium; line-height: normal;">
さらに、Fig.4(C)のTubulinの左から3レーン目と4レーン目の間にも編集の跡を見ることができる。</div>
<div style="font-family: 'MS PGothic'; font-size: medium; line-height: normal;">
<br /></div>
</div>
<div style="margin-bottom: 0.5em; margin-top: 0.5em;">
<span style="color: #274e13;"><span style="font-family: Arial, Helvetica, sans-serif;">Lanes 2, 3 and 4 (Ol, Az, and Hy) of tubulin blots in Fig.4 (A) and Fig.4(B) are similar to lanes 1, 2, and 3 (Ve, Ol, and Az) </span><span style="font-family: Arial, Helvetica, sans-serif; line-height: 1.0915em;">of tubulin blots</span><span style="font-family: Arial, Helvetica, sans-serif; line-height: 1.0915em;"> </span><span style="font-family: Arial, Helvetica, sans-serif; line-height: 1.0915em;">in Fig.4(C)</span><span style="font-family: Arial, Helvetica, sans-serif; line-height: 1.0915em;">,</span></span></div>
<div style="margin-bottom: 0.5em; margin-top: 0.5em;">
<span style="color: #274e13;"><span style="font-family: Arial, Helvetica, sans-serif;">and lanes 5, 6 and 7 (Ol+Ax, Ol+Hy, and WKY) of tubulin blots in Fig.4(A) and Fig.4(B) are similar to lanes 4, 5, and 6 (Hy, Ol+Az, and Ol+Hy) </span><span style="font-family: Arial, Helvetica, sans-serif; line-height: 1.0915em;">of tubulin blots</span><span style="font-family: Arial, Helvetica, sans-serif; line-height: 1.0915em;"> </span><span style="font-family: Arial, Helvetica, sans-serif; line-height: 1.0915em;">in Fig.4(C)</span><span style="font-family: Arial, Helvetica, sans-serif; line-height: 1.0915em;">.</span></span></div>
<div style="margin-bottom: 0.5em; margin-top: 0.5em;">
<span style="color: #274e13;"><span style="font-family: Arial, Helvetica, sans-serif;">There is discontinuity between lanes 4 and 5 of </span><span style="font-family: Arial, Helvetica, sans-serif; line-height: 1.0915em;">tubulin blots</span><span style="font-family: Arial, Helvetica, sans-serif; line-height: 1.0915em;"> </span><span style="font-family: Arial, Helvetica, sans-serif; line-height: 1.0915em;">in Fig.4(A) and Fig.4(B) between lanes 3 and 4 of </span><span style="font-family: Arial, Helvetica, sans-serif; line-height: 1.0915em;">tubulin blots</span><span style="font-family: Arial, Helvetica, sans-serif; line-height: 1.0915em;"> </span><span style="font-family: Arial, Helvetica, sans-serif; line-height: 1.0915em;">in Fig.4(C), which indicates deliberate image manipulation.</span></span><br />
<span style="color: #274e13;"><span style="font-family: Arial, Helvetica, sans-serif; line-height: 1.0915em;"><br /></span></span>
<br />
<div class="separator" style="clear: both; text-align: center;">
</div>
<div class="separator" style="clear: both; text-align: center;">
<br /></div>
<div class="separator" style="clear: both; text-align: center;">
<a href="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEh4ErsePFk0drH-D5AC2QPEgmUMcwS798_mw20Y2wImaz3HZn-Kx-P86wq1z2dc9-aj3xkykxaJmmq5qe6QwiF9CnUtEam2zrtXI5kYbfH_AL5DtmUGr8EmLVHhfG5_mpjao2Fg7oo7MAQ/s1600/1+copy.jpg" imageanchor="1" style="margin-left: 1em; margin-right: 1em;"><img border="0" height="400" src="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEh4ErsePFk0drH-D5AC2QPEgmUMcwS798_mw20Y2wImaz3HZn-Kx-P86wq1z2dc9-aj3xkykxaJmmq5qe6QwiF9CnUtEam2zrtXI5kYbfH_AL5DtmUGr8EmLVHhfG5_mpjao2Fg7oo7MAQ/s400/1+copy.jpg" width="242" /></a></div>
<br />
<div class="separator" style="clear: both; text-align: center;">
<a href="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEjPDhxmvyjGNngEx_5p5yuQ32-_ifS86CqDZUrupViftYzN1dmOw-JEX2p6Zme3hE5bXSGsdAhOwHnCKUb4_39NgnAScXPNE4OJcrPMLl8eWBfScWLhSIT6BXJzB43wiaFr_OZ3hoP6EWU/s1600/2+copy.jpg" imageanchor="1" style="margin-left: 1em; margin-right: 1em;"><img border="0" height="400" src="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEjPDhxmvyjGNngEx_5p5yuQ32-_ifS86CqDZUrupViftYzN1dmOw-JEX2p6Zme3hE5bXSGsdAhOwHnCKUb4_39NgnAScXPNE4OJcrPMLl8eWBfScWLhSIT6BXJzB43wiaFr_OZ3hoP6EWU/s400/2+copy.jpg" width="265" /></a></div>
<div class="separator" style="clear: both; text-align: center;">
<br /></div>
<div class="separator" style="clear: both; text-align: center;">
</div>
<div class="separator" style="clear: both; text-align: center;">
</div>
<div class="separator" style="clear: both; text-align: center;">
</div>
<br />
<div class="separator" style="clear: both; text-align: center;">
</div>
<div class="separator" style="clear: both; text-align: center;">
<br /></div>
<span style="color: #274e13;"><span style="font-family: Arial, Helvetica, sans-serif; line-height: 1.0915em;"><br /></span></span>
<br />
<div style="color: #666666; font-family: 'Trebuchet MS', Trebuchet, Verdana, sans-serif; font-size: 13.333333015441895px; line-height: 14.541666984558105px;">
<div style="font-size: 13.333333015441895px; line-height: 14.541666984558105px;">
<hr style="font-family: arial, helvetica, clean, sans-serif; font-size: 0.8465em; line-height: 14.541666984558105px;" />
</div>
</div>
</div>
<div style="margin-bottom: 0.5em; margin-top: 0.5em;">
<span style="line-height: normal;"> ・ Fig.4(A)とFig.4(B)のTubulilnの左から2,3,4,5,6,7レーン目の画像(Ol, Az, Hy, Ol+Ax, Ol+Hy, WKY)が、Fig.4(D)とFig.5(B)のTubulinの左から1,2,3,4,5,6レーン目の画像(Ve, Ol, Az, Hy, Ol+Az, Ol+Hy)に類似している。</span><br />
<span style="color: #274e13; font-family: Arial, Helvetica, sans-serif; line-height: 1.0915em;"><br /></span>
<span style="color: #274e13; font-family: Arial, Helvetica, sans-serif; line-height: 1.0915em;">Lanes 2, 3, 4, 5, 6, and 7 (Ol, Az, Hy, <span style="line-height: 1.0915em;">Ol+Ax, Ol+Hy, and WKY</span><span style="line-height: 1.0915em;">) of </span></span><span style="color: #274e13; font-family: Arial, Helvetica, sans-serif; line-height: 1.0915em;">tubulin blots</span><span style="color: #274e13; font-family: Arial, Helvetica, sans-serif; line-height: 1.0915em;"> </span><span style="color: #274e13; font-family: Arial, Helvetica, sans-serif; line-height: 1.0915em;"><span style="line-height: 1.0915em;">in Fig.4(A) and </span></span><span style="color: #274e13; font-family: Arial, Helvetica, sans-serif; line-height: 1.0915em;">Fig.4</span><span style="color: #274e13; font-family: Arial, Helvetica, sans-serif; line-height: 1.0915em;">(B) are similar to lanes 1, 2, 3, 4, 5, and 6 (Ve, Ol, Az, Hy, Ol+Az, and Ol+Hy) of </span><span style="color: #274e13; font-family: Arial, Helvetica, sans-serif; line-height: 1.0915em;">tubulin blots</span><span style="color: #274e13; font-family: Arial, Helvetica, sans-serif; line-height: 1.0915em;"> </span><span style="color: #274e13; font-family: Arial, Helvetica, sans-serif; line-height: 1.0915em;">in Fig.4(D) and Fig.5(B).</span></div>
<div style="margin-bottom: 0.5em; margin-top: 0.5em;">
<div>
<span style="color: #274e13;"><span style="font-family: Arial, Helvetica, sans-serif; line-height: 1.0915em;"><br /></span></span>
<br />
<div class="separator" style="clear: both; text-align: center;">
</div>
<div class="separator" style="clear: both; text-align: center;">
<a href="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEhA0Jh3M590kP8b5zjkDHjYVP4nHK5qOrRMZT1bacYs8WYH-_hAkLoMslqjL-B6BfHN2EdxTLn6aSp50MYM_YV5VvG2Fk_m4X-BAbc1NtM5O2vDVw3Dm_6fjbLUCwSMK75v9dT1YFL6j0E/s1600/3+copy.jpg" imageanchor="1" style="margin-left: 1em; margin-right: 1em;"><img border="0" height="400" src="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEhA0Jh3M590kP8b5zjkDHjYVP4nHK5qOrRMZT1bacYs8WYH-_hAkLoMslqjL-B6BfHN2EdxTLn6aSp50MYM_YV5VvG2Fk_m4X-BAbc1NtM5O2vDVw3Dm_6fjbLUCwSMK75v9dT1YFL6j0E/s400/3+copy.jpg" width="197" /></a></div>
<span style="color: #274e13;"><span style="font-family: Arial, Helvetica, sans-serif; line-height: 1.0915em;"><br /></span></span></div>
</div>
<div style="margin-bottom: 0.5em; margin-top: 0.5em;">
</div>
</div>
11jigenhttp://www.blogger.com/profile/03513633746083109180noreply@blogger.com0tag:blogger.com,1999:blog-2022612537151365301.post-14062777670331108742013-05-18T22:22:00.004+09:002013-05-18T23:13:50.105+09:00Advanced glycation end products activate a chymase-dependent angiotensin II-generating pathway in diabetic complications.<br />
<br />
<div class="MsoNormal" style="background: white; line-height: 17.4pt; margin-bottom: .0001pt; margin-bottom: 0in;">
<span style="font-family: Arial, sans-serif; font-size: 10pt;"><a href="http://www.ncbi.nlm.nih.gov/pubmed/?term=Circulation.+2006+Mar+14%3B113(10)%3A1353-60." title="Circulation."><span style="color: #660066; text-decoration: none; text-underline: none;">Circulation</span><span style="color: #660066;">.</span></a> 2006 Mar 14;113(10):1353-60. Epub 2006 Mar 6.<o:p></o:p></span></div>
<div class="MsoNormal" style="background: white; margin-bottom: 4.5pt; margin-left: 0in; margin-right: 0in; margin-top: 4.5pt; mso-line-height-alt: 13.5pt; mso-outline-level: 1;">
<b><span style="font-family: Arial, sans-serif; font-size: 15pt;">Advanced glycation end products activate a chymase-dependent angiotensin II-generating pathway in diabetic complications.<o:p></o:p></span></b></div>
<div class="MsoNormal" style="background-color: white; background-position: initial initial; background-repeat: initial initial; margin-bottom: 0.0001pt;">
<span style="color: #660066; font-family: Arial, sans-serif;">Koka V, Wang W, Huang XR, <a href="http://shokei-kim-mitsuyama.blogspot.com/">Kim-Mitsuyama S</a>, Truong LD, Lan HY.</span></div>
<div class="MsoNormal" style="background-color: white; background-position: initial initial; background-repeat: initial initial; line-height: 13.1pt; margin: 6pt 0in;">
<span style="font-family: Arial, sans-serif; font-size: 10pt;">Department of Medicine-Nephrology, Baylor College of Medicine, Houston, TX 77030, USA.<o:p></o:p></span></div>
<div class="MsoNormal" style="background-color: white; background-position: initial initial; background-repeat: initial initial; line-height: 13.1pt; margin: 6pt 0in;">
<a href="http://www.ncbi.nlm.nih.gov/pubmed/16520412">http://www.ncbi.nlm.nih.gov/pubmed/16520412</a></div>
<div class="MsoNormal" style="background-color: white; background-position: initial initial; background-repeat: initial initial; line-height: 13.1pt; margin: 6pt 0in;">
<a href="http://circ.ahajournals.org/content/113/10/1353.long">http://circ.ahajournals.org/content/113/10/1353.long</a></div>
<div class="MsoNormal" style="background-color: white; background-position: initial initial; background-repeat: initial initial; line-height: 13.1pt; margin: 6pt 0in;">
<br /></div>
<div class="MsoNormal" style="background-color: white; background-position: initial initial; background-repeat: initial initial; line-height: 13.1pt; margin: 6pt 0in;">
<span style="color: #38761d; font-family: 'Trebuchet MS', Trebuchet, Verdana, sans-serif; line-height: 20px;">"</span><span style="color: #38761d; font-family: 'Trebuchet MS', Trebuchet, Verdana, sans-serif; line-height: 20px;">GAPDH</span><span style="color: #38761d; font-family: 'Trebuchet MS', Trebuchet, Verdana, sans-serif; line-height: 20px;">"</span><span style="color: #38761d; font-family: 'Trebuchet MS', Trebuchet, Verdana, sans-serif; line-height: 20px;"> in <a href="http://circ.ahajournals.org/content/113/10/1353/F3.large.jpg">Fig.3(B)</a> is similar to </span><span style="color: #38761d; font-family: 'Trebuchet MS', Trebuchet, Verdana, sans-serif; line-height: 20px;">"</span><span style="color: #38761d; font-family: 'Trebuchet MS', Trebuchet, Verdana, sans-serif; line-height: 20px;">GAPDH</span><span style="color: #38761d; font-family: 'Trebuchet MS', Trebuchet, Verdana, sans-serif; line-height: 20px;">"</span><span style="color: #38761d; font-family: 'Trebuchet MS', Trebuchet, Verdana, sans-serif; line-height: 20px;"> in <a href="http://circ.ahajournals.org/content/113/10/1353/F4.large.jpg">Fig.4(B)</a>.</span><br />
<span style="background-position: initial initial; background-repeat: initial initial; color: #333333; font-family: Georgia, serif; font-size: 16.5pt; line-height: 115%;">( <a href="http://circ.ahajournals.org/content/113/10/1353/F3.large.jpg">Fig.3(B) </a>GAPDH </span><span lang="JA" style="background-position: initial initial; background-repeat: initial initial; color: #333333; font-family: 'MS 明朝', serif; font-size: 16.5pt; line-height: 115%;">が、</span><span style="background-position: initial initial; background-repeat: initial initial; color: #333333; font-family: Georgia, serif; font-size: 16.5pt; line-height: 115%;"><a href="http://circ.ahajournals.org/content/113/10/1353/F4.large.jpg">Fig.4(B)</a>GAPDH</span><span lang="JA" style="background-position: initial initial; background-repeat: initial initial; color: #333333; font-family: 'MS 明朝', serif; font-size: 16.5pt; line-height: 115%;">に類似 )</span><br />
<span lang="JA" style="background-position: initial initial; background-repeat: initial initial; color: #333333; font-family: 'MS 明朝', serif; font-size: 16.5pt; line-height: 115%;"><br /></span>
<br />
<div class="separator" style="clear: both; text-align: center;">
<a href="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEimgZB2kW_RLjUAIdEyxZi4tLnfmJdU_h1f3OLD1Xe4BuxewCuZNENwFHYz51a3YZI7p-34Z4G2nONLfg4RBIqxjPXr-i_Uq8-CTgS4mE2IKgIoHuCLKUrOncWDvL46O50JLsLRRKXvM_t2/s1600/Fig3,4.jpg" imageanchor="1" style="margin-left: 1em; margin-right: 1em;"><img border="0" height="233" src="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEimgZB2kW_RLjUAIdEyxZi4tLnfmJdU_h1f3OLD1Xe4BuxewCuZNENwFHYz51a3YZI7p-34Z4G2nONLfg4RBIqxjPXr-i_Uq8-CTgS4mE2IKgIoHuCLKUrOncWDvL46O50JLsLRRKXvM_t2/s400/Fig3,4.jpg" width="400" /></a></div>
<div>
<br /></div>
</div>
11jigenhttp://www.blogger.com/profile/03513633746083109180noreply@blogger.com0tag:blogger.com,1999:blog-2022612537151365301.post-19839873710421875732013-05-18T22:22:00.001+09:002013-05-18T22:22:31.988+09:00Beneficial effect of candesartan on rat diastolic heart failure.<br />
<br />
<div class="cit" style="font-family: arial, helvetica, clean, sans-serif; font-size: 0.8465em; line-height: 1.45em;">
<span role="menubar">J Pharmacol Sci.</span> 2005 Aug;98(4):372-9. Epub 2005 Jul 29.</div>
<h1 style="font-family: arial, helvetica, clean, sans-serif; font-size: 1.231em; line-height: 1.125em; margin: 0.375em 0px;">
Beneficial effect of candesartan on rat diastolic heart failure.</h1>
<div class="auths">
<span style="font-family: arial, helvetica, clean, sans-serif;"><span style="font-size: 14.44444465637207px; line-height: 23.19444465637207px;">Wake R, <a href="http://shokei-kim-mitsuyama.blogspot.com/">Kim-Mitsuyama S</a>, Izumi Y, Yoshida K, Izumiya Y, Yukimura T, Shiota M, Yoshiyama M, Yoshikawa J, Iwao H.</span></span></div>
<div class="aff" style="font-family: arial, helvetica, clean, sans-serif; line-height: 1.0915em;">
<h3 class="label" style="color: #724128; font-size: 1.0769em; height: 1px; left: -10000px; line-height: 1.2857; margin: 1.2856em 0px 0.6428em; overflow: hidden; position: absolute; top: auto; width: 1px;">
Source</h3>
<div style="font-size: 0.8465em; margin-bottom: 0.5em; margin-top: 0.5em;">
Department of Pharmacology, Osaka City University Graduate School of Medical Sciences, Osaka 545-8585, Japan.</div>
<div style="font-size: 0.8465em; margin-bottom: 0.5em; margin-top: 0.5em;">
<a href="http://www.ncbi.nlm.nih.gov/pubmed/16079469">http://www.ncbi.nlm.nih.gov/pubmed/16079469</a></div>
<div style="font-size: 0.8465em; margin-bottom: 0.5em; margin-top: 0.5em;">
<a href="https://www.jstage.jst.go.jp/article/jphs/98/4/98_4_372/_article">https://www.jstage.jst.go.jp/article/jphs/98/4/98_4_372/_article</a></div>
<div style="font-size: 0.8465em; margin-bottom: 0.5em; margin-top: 0.5em;">
<a href="https://www.jstage.jst.go.jp/article/jphs/98/4/98_4_372/_pdf">https://www.jstage.jst.go.jp/article/jphs/98/4/98_4_372/_pdf</a></div>
<div style="margin-bottom: 0.5em; margin-top: 0.5em;">
<div style="font-size: 0.8465em;">
<br /></div>
<span style="background-color: white; color: #38761d; font-family: 'Trebuchet MS', Trebuchet, Verdana, sans-serif; line-height: 20px;">Fig.4 - </span><span style="background-color: white; color: #38761d; font-family: 'Trebuchet MS', Trebuchet, Verdana, sans-serif; line-height: 20px;">"</span><span style="background-color: white; color: #38761d; font-family: 'Trebuchet MS', Trebuchet, Verdana, sans-serif; line-height: 20px;">BNP</span><span style="background-color: white; color: #38761d; font-family: 'Trebuchet MS', Trebuchet, Verdana, sans-serif; line-height: 20px;">"</span><span style="background-color: white; color: #38761d; font-family: 'Trebuchet MS', Trebuchet, Verdana, sans-serif; line-height: 20px;"> is similar to </span><span style="background-color: white; color: #38761d; font-family: 'Trebuchet MS', Trebuchet, Verdana, sans-serif; line-height: 20px;">"</span><span style="background-color: white; color: #38761d; font-family: 'Trebuchet MS', Trebuchet, Verdana, sans-serif; line-height: 20px;">MCP-1</span><span style="background-color: white; color: #38761d; font-family: 'Trebuchet MS', Trebuchet, Verdana, sans-serif; line-height: 20px;">"</span><span style="background-color: white; color: #38761d; font-family: 'Trebuchet MS', Trebuchet, Verdana, sans-serif; line-height: 20px;">.</span><span style="background-color: white; color: #38761d; font-family: 'Trebuchet MS', Trebuchet, Verdana, sans-serif; line-height: 20px;"> </span></div>
<div style="margin-bottom: 0.5em; margin-top: 0.5em;">
</div>
<div class="MsoNormal">
<span style="background-position: initial initial; background-repeat: initial initial; color: #333333; font-family: Georgia, serif; font-size: 16.5pt; line-height: 115%;">( Fig.4</span><span lang="JA" style="background-position: initial initial; background-repeat: initial initial; color: #333333; font-family: 'MS 明朝', serif; font-size: 16.5pt; line-height: 115%;">の</span><span style="background-position: initial initial; background-repeat: initial initial; color: #333333; font-family: Georgia, serif; font-size: 16.5pt; line-height: 115%;">BNP</span><span lang="JA" style="background-position: initial initial; background-repeat: initial initial; color: #333333; font-family: 'MS 明朝', serif; font-size: 16.5pt; line-height: 115%;">と</span><span style="background-position: initial initial; background-repeat: initial initial; color: #333333; font-family: Georgia, serif; font-size: 16.5pt; line-height: 115%;">MCP-1</span><span lang="JA" style="background-position: initial initial; background-repeat: initial initial; color: #333333; font-family: 'MS 明朝', serif; font-size: 16.5pt; line-height: 115%;">が類似</span><span style="background-position: initial initial; background-repeat: initial initial; color: #333333; font-family: Georgia, serif; font-size: 16.5pt; line-height: 115%;"> )<span style="font-size: 0.8465em;"><o:p></o:p></span></span></div>
</div>
<br />
<div class="separator" style="clear: both; text-align: center;">
<a href="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEhFhFWLCXt3e8OOIlJx-GzhlgB5Klm8wv8bZmAo_TIn1cp5HtlTFNPeSZfTKB6C8Cn5Sk0q4bTG8Tf1fEzS9cEmYD63H_SIxkG7FtKeXtFROSlqQubBZ6haoeWe3sE2Paowbc4WtnDVji-e/s1600/JPS+2005+Fig4.jpg" imageanchor="1" style="margin-left: 1em; margin-right: 1em;"><img border="0" height="220" src="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEhFhFWLCXt3e8OOIlJx-GzhlgB5Klm8wv8bZmAo_TIn1cp5HtlTFNPeSZfTKB6C8Cn5Sk0q4bTG8Tf1fEzS9cEmYD63H_SIxkG7FtKeXtFROSlqQubBZ6haoeWe3sE2Paowbc4WtnDVji-e/s400/JPS+2005+Fig4.jpg" width="400" /></a></div>
<div>
<br /></div>
11jigenhttp://www.blogger.com/profile/03513633746083109180noreply@blogger.com0tag:blogger.com,1999:blog-2022612537151365301.post-79810277568556022722013-05-18T22:20:00.002+09:002013-05-18T22:20:14.771+09:00Excess aldosterone under normal salt diet induces cardiac hypertrophy and infiltration via oxidative stress.<br />
<br />
<div class="MsoNormal" style="background: white; line-height: 17.4pt; margin-bottom: .0001pt; margin-bottom: 0in;">
<span style="font-family: Arial, sans-serif; font-size: 10pt;"><span style="color: #660066;">Hypertens Res.</span> 2005 May;28(5):447-55.<o:p></o:p></span></div>
<div class="MsoNormal" style="background: white; margin-bottom: 4.5pt; margin-left: 0in; margin-right: 0in; margin-top: 4.5pt; mso-line-height-alt: 13.5pt; mso-outline-level: 1;">
<b><span style="font-family: Arial, sans-serif; font-size: 15pt;">Excess aldosterone under normal salt diet induces cardiac hypertrophy and infiltration via oxidative stress.<o:p></o:p></span></b></div>
<div class="MsoNormal" style="background-color: white; background-position: initial initial; background-repeat: initial initial; margin-bottom: 0.0001pt;">
<span style="color: #660066; font-family: Arial, sans-serif;">Yoshida K, <a href="http://shokei-kim-mitsuyama.blogspot.com/">Kim-Mitsuyama S</a>, Wake R, Izumiya Y, Izumi Y, Yukimura T, Ueda M, Yoshiyama M, Iwao H.</span></div>
<div class="MsoNormal" style="background-color: white; line-height: 13.1pt; margin: 6pt 0in;">
<span style="font-family: Arial, sans-serif; font-size: 10pt;">Department of Pharmacology, Osaka City University Graduate School of Medical Science, Osaka, Japan.</span><span style="font-family: Arial, sans-serif; font-size: 10pt;"><o:p></o:p></span></div>
<div class="MsoNormal" style="background-color: white; line-height: 13.1pt; margin: 6pt 0in;">
<span style="font-family: Arial, sans-serif; font-size: 10pt;"> </span><a href="http://www.ncbi.nlm.nih.gov/pubmed/16156509" style="background-color: transparent;">http://www.ncbi.nlm.nih.gov/pubmed/16156509</a></div>
<div class="MsoNormal" style="background-color: white; line-height: 13.1pt; margin: 6pt 0in;">
<a href="http://www.nature.com/hr/journal/v28/n5/full/hr200556a.html">http://www.nature.com/hr/journal/v28/n5/full/hr200556a.html</a></div>
<div class="MsoNormal" style="background-color: white; line-height: 13.1pt; margin: 6pt 0in;">
<a href="http://www.nature.com/hr/journal/v28/n5/pdf/hr200556a.pdf">http://www.nature.com/hr/journal/v28/n5/pdf/hr200556a.pdf</a></div>
<div class="MsoNormal" style="background-color: white; line-height: 13.1pt; margin: 6pt 0in;">
<br />
<span style="color: #38761d; font-family: 'Trebuchet MS', Trebuchet, Verdana, sans-serif; line-height: 20px;">Fig.2B - </span><span style="color: #38761d; font-family: 'Trebuchet MS', Trebuchet, Verdana, sans-serif; line-height: 20px;">"</span><span style="color: #38761d; font-family: 'Trebuchet MS', Trebuchet, Verdana, sans-serif; line-height: 20px;">Con</span><span style="color: #38761d; font-family: 'Trebuchet MS', Trebuchet, Verdana, sans-serif; line-height: 20px;">"</span><span style="color: #38761d; font-family: 'Trebuchet MS', Trebuchet, Verdana, sans-serif; line-height: 20px;"> is similar to </span><span style="color: #38761d; font-family: 'Trebuchet MS', Trebuchet, Verdana, sans-serif; line-height: 20px;">"</span><span style="color: #38761d; font-family: 'Trebuchet MS', Trebuchet, Verdana, sans-serif; line-height: 20px;">ALD/Spi </span><span style="color: #38761d; font-family: 'Trebuchet MS', Trebuchet, Verdana, sans-serif; line-height: 20px;">"</span><span style="color: #38761d; font-family: 'Trebuchet MS', Trebuchet, Verdana, sans-serif; line-height: 20px;">.</span></div>
<div class="MsoNormal" style="background-color: white; line-height: 13.1pt; margin: 6pt 0in;">
</div>
<div class="MsoNormal">
<span style="background-position: initial initial; background-repeat: initial initial; color: #333333; font-family: Georgia, serif; font-size: 16.5pt; line-height: 115%;">( Fig.2B</span><span lang="JA" style="background-position: initial initial; background-repeat: initial initial; color: #333333; font-family: 'MS 明朝', serif; font-size: 16.5pt; line-height: 115%;">の</span><span style="background-position: initial initial; background-repeat: initial initial; color: #333333; font-family: Georgia, serif; font-size: 16.5pt; line-height: 115%;">Con</span><span lang="JA" style="background-position: initial initial; background-repeat: initial initial; color: #333333; font-family: 'MS 明朝', serif; font-size: 16.5pt; line-height: 115%;">と</span><span style="background-position: initial initial; background-repeat: initial initial; color: #333333; font-family: Georgia, serif; font-size: 16.5pt; line-height: 115%;">ALD/Spi</span><span lang="JA" style="background-position: initial initial; background-repeat: initial initial; color: #333333; font-family: 'MS 明朝', serif; font-size: 16.5pt; line-height: 115%;">が類似 )</span><span style="background-position: initial initial; background-repeat: initial initial; color: #333333; font-family: Georgia, serif; font-size: 16.5pt; line-height: 115%;"><o:p></o:p></span></div>
<br />
<div class="separator" style="clear: both; text-align: center;">
<a href="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEgaXZo3FV9n9Lb0dWG5r4eDIBfq5g9WM-cUlMUajDt79jcdaltWR_JEDNkRC53zAjT18UPBV_nnf1Lhazt0HwB2aw2XHpWJOWEha_Y4hfROtH4ySflypjitQlW9oVajCLTidxWyXyy_bQd_/s1600/Hypertension+Res+2005+Fig2%E3%81%AE%E3%82%B3%E3%83%94%E3%83%BC.jpg" imageanchor="1" style="margin-left: 1em; margin-right: 1em;"><img border="0" height="363" src="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEgaXZo3FV9n9Lb0dWG5r4eDIBfq5g9WM-cUlMUajDt79jcdaltWR_JEDNkRC53zAjT18UPBV_nnf1Lhazt0HwB2aw2XHpWJOWEha_Y4hfROtH4ySflypjitQlW9oVajCLTidxWyXyy_bQd_/s400/Hypertension+Res+2005+Fig2%E3%81%AE%E3%82%B3%E3%83%94%E3%83%BC.jpg" width="400" /></a></div>
<div>
<br /></div>
11jigenhttp://www.blogger.com/profile/03513633746083109180noreply@blogger.com0tag:blogger.com,1999:blog-2022612537151365301.post-6578668083199418392013-05-18T22:19:00.000+09:002013-05-18T22:19:58.355+09:00Apoptosis signal-regulating kinase 1 plays a pivotal role in angiotensin II-induced cardiac hypertrophy and remodeling.<br />
<span style="color: #660066; font-family: Arial, sans-serif; font-size: 10pt;">Circ Res.</span><span style="font-family: Arial, sans-serif; font-size: 10pt;"> 2003 Oct 31;93(9):874-83. Epub 2003 Oct 9.</span><br />
<div class="MsoNormal" style="background: white; margin-bottom: 4.5pt; margin-left: 0in; margin-right: 0in; margin-top: 4.5pt; mso-line-height-alt: 13.5pt; mso-outline-level: 1;">
<b><span style="font-family: Arial, sans-serif; font-size: 15pt;">Apoptosis signal-regulating kinase 1 plays a pivotal role in angiotensin II-induced cardiac hypertrophy and remodeling.<o:p></o:p></span></b></div>
<div class="MsoNormal" style="background-color: white; background-position: initial initial; background-repeat: initial initial; margin-bottom: 0.0001pt;">
Izumiya Y, <a href="http://shokei-kim-mitsuyama.blogspot.com/">Kim S</a>, Izumi Y, Yoshida K, Yoshiyama M, Matsuzawa A, Ichijo H, Iwao H.</div>
<div class="MsoNormal" style="background-color: white; background-position: initial initial; background-repeat: initial initial; margin-bottom: 0.0001pt;">
<span style="font-family: Arial, sans-serif; font-size: 10pt; line-height: 13.1pt;">Department of Pharmacology, Osaka City University Graduate School of Medical Science, 1-4-3 Asahimachi, Abeno, Osaka 545-8585, Japan.</span></div>
<div class="MsoNormal" style="background-color: white; background-position: initial initial; background-repeat: initial initial; margin-bottom: 0.0001pt;">
<span style="font-family: Arial, sans-serif; font-size: 10pt; line-height: 13.1pt;"><br /></span></div>
<div class="MsoNormal" style="background-color: white; background-position: initial initial; background-repeat: initial initial; margin-bottom: 0.0001pt;">
<a href="http://www.ncbi.nlm.nih.gov/pubmed/14551246">http://www.ncbi.nlm.nih.gov/pubmed/14551246</a></div>
<div class="MsoNormal" style="background-color: white; background-position: initial initial; background-repeat: initial initial; margin-bottom: 0.0001pt;">
<a href="http://circres.ahajournals.org/content/93/9/874.long">http://circres.ahajournals.org/content/93/9/874.long</a></div>
<div class="MsoNormal" style="background-color: white; background-position: initial initial; background-repeat: initial initial; margin-bottom: 0.0001pt;">
<br /></div>
<div class="MsoNormal" style="background-color: white; background-position: initial initial; background-repeat: initial initial; margin-bottom: 0.0001pt;">
<br />
<span style="background-color: white; color: #38761d; font-family: 'Trebuchet MS', Trebuchet, Verdana, sans-serif; line-height: 20px;"><a href="http://circres.ahajournals.org/content/93/9/874/F4.large.jpg">Fig.4A</a> - "Wild" image is similar to </span><span style="background-color: white; color: #38761d; font-family: 'Trebuchet MS', Trebuchet, Verdana, sans-serif; line-height: 20px;">"</span><span style="background-color: white; color: #38761d; font-family: 'Trebuchet MS', Trebuchet, Verdana, sans-serif; line-height: 20px;">ASK1 -/-</span><span style="background-color: white; color: #38761d; font-family: 'Trebuchet MS', Trebuchet, Verdana, sans-serif; line-height: 20px;">"</span><span style="background-color: white; color: #38761d; font-family: 'Trebuchet MS', Trebuchet, Verdana, sans-serif; line-height: 20px;">.</span><span style="background-color: white; color: #38761d; font-family: 'Trebuchet MS', Trebuchet, Verdana, sans-serif; line-height: 20px;"> </span><br />
<span style="background: white; color: #333333; font-family: "Georgia","serif"; font-size: 16.5pt; line-height: 115%; mso-ansi-language: EN-US; mso-bidi-font-family: "Times New Roman"; mso-bidi-language: AR-SA; mso-bidi-theme-font: minor-bidi; mso-fareast-font-family: "MS 明朝"; mso-fareast-language: JA; mso-fareast-theme-font: minor-fareast;">( <a href="http://circres.ahajournals.org/content/93/9/874/F4.large.jpg">Fig.4A</a></span><span lang="JA" style="background: white; color: #333333; font-family: "MS 明朝","serif"; font-size: 16.5pt; line-height: 115%; mso-ansi-language: EN-US; mso-ascii-font-family: Georgia; mso-bidi-font-family: "Times New Roman"; mso-bidi-language: AR-SA; mso-bidi-theme-font: minor-bidi; mso-fareast-language: JA; mso-fareast-theme-font: minor-fareast; mso-hansi-font-family: Georgia;">の</span><span style="background: white; color: #333333; font-family: "Georgia","serif"; font-size: 16.5pt; line-height: 115%; mso-ansi-language: EN-US; mso-bidi-font-family: "Times New Roman"; mso-bidi-language: AR-SA; mso-bidi-theme-font: minor-bidi; mso-fareast-font-family: "MS 明朝"; mso-fareast-language: JA; mso-fareast-theme-font: minor-fareast;">Wild</span><span lang="JA" style="background: white; color: #333333; font-family: "MS 明朝","serif"; font-size: 16.5pt; line-height: 115%; mso-ansi-language: EN-US; mso-ascii-font-family: Georgia; mso-bidi-font-family: "Times New Roman"; mso-bidi-language: AR-SA; mso-bidi-theme-font: minor-bidi; mso-fareast-language: JA; mso-fareast-theme-font: minor-fareast; mso-hansi-font-family: Georgia;">と</span><span style="background: white; color: #333333; font-family: "Georgia","serif"; font-size: 16.5pt; line-height: 115%; mso-ansi-language: EN-US; mso-bidi-font-family: "Times New Roman"; mso-bidi-language: AR-SA; mso-bidi-theme-font: minor-bidi; mso-fareast-font-family: "MS 明朝"; mso-fareast-language: JA; mso-fareast-theme-font: minor-fareast;">ASK1-/-</span><span lang="JA" style="background: white; color: #333333; font-family: "MS 明朝","serif"; font-size: 16.5pt; line-height: 115%; mso-ansi-language: EN-US; mso-ascii-font-family: Georgia; mso-bidi-font-family: "Times New Roman"; mso-bidi-language: AR-SA; mso-bidi-theme-font: minor-bidi; mso-fareast-language: JA; mso-fareast-theme-font: minor-fareast; mso-hansi-font-family: Georgia;">の組織切片画像が類似。同一個体由来の組織切片のもので、スライス位置が違うだけと思われる</span><span lang="JA" style="background: white; color: #333333; font-family: "MS 明朝","serif"; font-size: 16.5pt; line-height: 115%; mso-ansi-language: EN-US; mso-bidi-font-family: "MS 明朝"; mso-bidi-language: AR-SA; mso-fareast-language: JA;">。 )</span><br />
<span lang="JA" style="background: white; color: #333333; font-family: "MS 明朝","serif"; font-size: 16.5pt; line-height: 115%; mso-ansi-language: EN-US; mso-bidi-font-family: "MS 明朝"; mso-bidi-language: AR-SA; mso-fareast-language: JA;"><br /></span>
<div class="separator" style="clear: both; text-align: center;">
<a href="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEhLEziIFdm1FNiqBA_JPT_XAiAg2mdP48_VSPCAP8NR4VaZumsoan8vO-Z8ThmkthMVBKHjnAedrYRgvAX_OEejUJo9_Vw28ZBA4Lwpz0BVSNkmzbzh2xUeGbZCPNArtxqjaU6YU5Yu_WQz/s1600/Circ+Res+2003+Fig4.jpg" imageanchor="1" style="margin-left: 1em; margin-right: 1em;"><img border="0" height="400" src="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEhLEziIFdm1FNiqBA_JPT_XAiAg2mdP48_VSPCAP8NR4VaZumsoan8vO-Z8ThmkthMVBKHjnAedrYRgvAX_OEejUJo9_Vw28ZBA4Lwpz0BVSNkmzbzh2xUeGbZCPNArtxqjaU6YU5Yu_WQz/s400/Circ+Res+2003+Fig4.jpg" width="283" /></a></div>
<div>
<br /></div>
</div>
11jigenhttp://www.blogger.com/profile/03513633746083109180noreply@blogger.com0tag:blogger.com,1999:blog-2022612537151365301.post-39879429685511930952013-05-18T22:18:00.005+09:002013-05-18T22:18:29.674+09:00Differential contribution of three mitogen-activated protein kinases to PDGF-BB-induced mesangial cell proliferation and gene expression.<br />
<br />
<div class="cit" style="background-color: white; font-family: arial, helvetica, clean, sans-serif; font-size: 0.8465em; line-height: 1.45em;">
<span role="menubar">J Am Soc Nephrol.</span> 2003 Mar;14(3):584-92.</div>
<h1 style="background-color: white; font-family: arial, helvetica, clean, sans-serif; font-size: 1.231em; line-height: 1.125em; margin: 0.375em 0px;">
Differential contribution of three mitogen-activated protein kinases to PDGF-BB-induced mesangial cell proliferation and gene expression.</h1>
<div class="auths" style="background-color: white;">
<span style="font-family: arial, helvetica, clean, sans-serif;"><span style="font-size: 14.44444465637207px;">Kawano H, <a href="http://shokei-kim-mitsuyama.blogspot.com/">Kim S</a>, Ohta K, Nakao T, Miyazaki H, Nakatani T, Iwao H.</span></span></div>
<div class="aff" style="background-color: white; font-family: arial, helvetica, clean, sans-serif; font-size: 0.8465em; line-height: 1.0915em;">
<h3 class="label" style="color: #724128; font-size: 1.0769em; height: 1px; left: -10000px; line-height: 1.2857; margin: 1.2856em 0px 0.6428em; overflow: hidden; position: absolute; top: auto; width: 1px;">
Source</h3>
<div style="margin-bottom: 0.5em; margin-top: 0.5em;">
Department of Pharmacology, Osaka City University Medical School, Japan.</div>
</div>
<br />
<div class="aff" style="line-height: 1.0915em;">
<div style="background-color: white; font-family: arial, helvetica, clean, sans-serif; font-size: 20px; margin-bottom: 0.5em; margin-top: 0.5em;">
<a href="http://www.ncbi.nlm.nih.gov/pubmed/12595493">http://www.ncbi.nlm.nih.gov/pubmed/12595493</a></div>
<div style="background-color: white; font-family: arial, helvetica, clean, sans-serif; font-size: 20px; margin-bottom: 0.5em; margin-top: 0.5em;">
<a href="http://jasn.asnjournals.org/content/14/3/584.long">http://jasn.asnjournals.org/content/14/3/584.long</a></div>
<div style="background-color: white; font-family: arial, helvetica, clean, sans-serif; font-size: 20px; margin-bottom: 0.5em; margin-top: 0.5em;">
<br /></div>
<div style="background-color: white; font-family: arial, helvetica, clean, sans-serif; margin-bottom: 0.5em; margin-top: 0.5em;">
<span style="color: #38761d; font-family: 'Trebuchet MS', Trebuchet, Verdana, sans-serif; line-height: 18px;"><a href="http://jasn.asnjournals.org/content/14/3/584/F1.large.jpg">Fig.1C</a> - </span><span style="color: #38761d; font-family: 'Trebuchet MS', Trebuchet, Verdana, sans-serif; line-height: 20px;">Image of 3 lanes of </span><span style="color: #38761d; font-family: 'Trebuchet MS', Trebuchet, Verdana, sans-serif; line-height: 20px;">"</span><span style="color: #38761d; font-family: 'Trebuchet MS', Trebuchet, Verdana, sans-serif; line-height: 20px;">ERK</span><span style="color: #38761d; font-family: 'Trebuchet MS', Trebuchet, Verdana, sans-serif; line-height: 20px;">"</span><span style="color: #38761d; font-family: 'Trebuchet MS', Trebuchet, Verdana, sans-serif; line-height: 20px;"> is similar to that of </span><span style="color: #38761d; font-family: 'Trebuchet MS', Trebuchet, Verdana, sans-serif; line-height: 20px;">"p38</span><span style="color: #38761d; font-family: 'Trebuchet MS', Trebuchet, Verdana, sans-serif; line-height: 20px;">".</span></div>
<div style="margin-bottom: 0.5em; margin-top: 0.5em;">
<span style="background-color: white;"><span style="font-family: Arial, Helvetica, sans-serif;">( <a href="http://jasn.asnjournals.org/content/14/3/584/F1.large.jpg">Fig. 1C</a><span style="line-height: normal;">のERKの3レーンとp38の3レーンが類似。</span></span></span><br />
<span style="background-color: white;"><span style="font-family: Arial, Helvetica, sans-serif;"><span style="line-height: normal;">濃さあるいはコントラストが変更されており、完全一致はしない。</span>)</span></span><br />
<span style="background-color: white;"><span style="font-family: Arial, Helvetica, sans-serif;"><br /></span></span>
<div class="separator" style="clear: both; text-align: center;">
<a href="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEj6R2k3Tt13tIzRoKFeCZ_9XvsA7ikXgKAPRmgjqdliJcMWvc6LAuEI4c_hDkxXdWteGC8do9sqv423hsy6rBSlySfZs1VonFGGzrYb2AUkO_Nr_DaM1GhFBo0SiSSfhq1txP3mJfkAK33l/s1600/J+Am+Soc+Nephrol+2003.jpg" imageanchor="1" style="margin-left: 1em; margin-right: 1em;"><img border="0" height="267" src="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEj6R2k3Tt13tIzRoKFeCZ_9XvsA7ikXgKAPRmgjqdliJcMWvc6LAuEI4c_hDkxXdWteGC8do9sqv423hsy6rBSlySfZs1VonFGGzrYb2AUkO_Nr_DaM1GhFBo0SiSSfhq1txP3mJfkAK33l/s400/J+Am+Soc+Nephrol+2003.jpg" width="400" /></a></div>
<div>
<br /></div>
</div>
</div>
11jigenhttp://www.blogger.com/profile/03513633746083109180noreply@blogger.com0tag:blogger.com,1999:blog-2022612537151365301.post-79385477656737562102013-05-18T22:18:00.002+09:002013-05-18T22:18:13.380+09:00Important role of angiotensin II-mediated c-Jun NH(2)-terminal kinase activation in cardiac hypertrophy in hypertensive rats.<br />
<span style="color: #660066; font-family: Arial, sans-serif; font-size: 10pt;">Hypertension.</span><span style="font-family: Arial, sans-serif; font-size: 10pt;"> 2000 Oct;36(4):511-6.</span><br />
<div class="MsoNormal" style="background: white; margin-bottom: 4.5pt; margin-left: 0in; margin-right: 0in; margin-top: 4.5pt; mso-line-height-alt: 13.5pt; mso-outline-level: 1;">
<b><span style="font-family: Arial, sans-serif; font-size: 15pt;">Important role of angiotensin II-mediated c-Jun NH(2)-terminal kinase activation in cardiac hypertrophy in hypertensive rats.<o:p></o:p></span></b></div>
<div class="MsoNormal" style="background-color: white; background-position: initial initial; background-repeat: initial initial; margin-bottom: 0.0001pt;">
<span style="color: #660066; font-family: Arial, sans-serif;">Izumi Y, <a href="http://shokei-kim-mitsuyama.blogspot.com/">Kim S</a>, Zhan Y, Namba M, Yasumoto H, Iwao H.</span></div>
<div class="MsoNormal" style="background-color: white; background-position: initial initial; background-repeat: initial initial; line-height: 13.1pt; margin: 6pt 0in;">
<span style="font-family: Arial, sans-serif; font-size: 10pt;">Department of Pharmacology, Osaka City University Medical School, Osaka 545-8585, Japan.<o:p></o:p></span></div>
<div class="MsoNormal" style="background-color: white; background-position: initial initial; background-repeat: initial initial; line-height: 13.1pt; margin: 6pt 0in;">
<a href="http://www.ncbi.nlm.nih.gov/pubmed/11040228">http://www.ncbi.nlm.nih.gov/pubmed/11040228</a></div>
<div class="MsoNormal" style="background-color: white; background-position: initial initial; background-repeat: initial initial; line-height: 13.1pt; margin: 6pt 0in;">
<a href="http://hyper.ahajournals.org/content/36/4/511.long">http://hyper.ahajournals.org/content/36/4/511.long</a></div>
<div class="MsoNormal" style="background-color: white; background-position: initial initial; background-repeat: initial initial; line-height: 13.1pt; margin: 6pt 0in;">
<br />
<span style="color: #38761d; font-family: 'Trebuchet MS', Trebuchet, Verdana, sans-serif; line-height: 20px;">Fig.2 - The left lane of </span><span style="color: #38761d; font-family: 'Trebuchet MS', Trebuchet, Verdana, sans-serif; line-height: 20px;">"</span><span style="color: #38761d; font-family: 'Trebuchet MS', Trebuchet, Verdana, sans-serif; line-height: 20px;">ERK-Lo</span><span style="color: #38761d; font-family: 'Trebuchet MS', Trebuchet, Verdana, sans-serif; line-height: 20px;">"</span><span style="color: #38761d; font-family: 'Trebuchet MS', Trebuchet, Verdana, sans-serif; line-height: 20px;"> in the Fig.2 is similar to the right lane of </span><span style="color: #38761d; font-family: 'Trebuchet MS', Trebuchet, Verdana, sans-serif; line-height: 20px;">"ERK-W</span><span style="color: #38761d; font-family: 'Trebuchet MS', Trebuchet, Verdana, sans-serif; line-height: 20px;">" in Fig.4.</span><span style="color: #38761d; font-family: 'Trebuchet MS', Trebuchet, Verdana, sans-serif; line-height: 20px;"> </span></div>
<div class="MsoNormal" style="background-color: white; background-position: initial initial; background-repeat: initial initial; line-height: 13.1pt; margin: 6pt 0in;">
<span style="background-position: initial initial; background-repeat: initial initial; color: #333333; font-family: Georgia, serif; font-size: 16.5pt; line-height: 115%;">( <a href="http://hyper.ahajournals.org/content/36/4/511/F2.large.jpg">Fig.2</a> ERK-Lo </span><span lang="JA" style="background-position: initial initial; background-repeat: initial initial; color: #333333; font-family: 'MS 明朝', serif; font-size: 16.5pt; line-height: 115%;">左列、</span><span style="background-position: initial initial; background-repeat: initial initial; color: #333333; font-family: Georgia, serif; font-size: 16.5pt; line-height: 115%;"><a href="http://hyper.ahajournals.org/content/36/4/511/F4.large.jpg">Fig.4</a> ERK-W </span><span lang="JA" style="background-position: initial initial; background-repeat: initial initial; color: #333333; font-family: 'MS 明朝', serif; font-size: 16.5pt; line-height: 115%;">右列が類似。 )</span><br />
<span lang="JA" style="background-position: initial initial; background-repeat: initial initial; color: #333333; font-family: 'MS 明朝', serif; font-size: 16.5pt; line-height: 115%;"><br /></span>
<div class="separator" style="clear: both; text-align: center;">
</div>
<div class="separator" style="clear: both; text-align: center;">
<a href="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEjlzqGbCymFwhydUXplkLK3EVGsNss2cTiahda9V3elP97_VZig8nd0PjUDRvW6RLUSCHxnJ-eXIuK0YQ5RmXJgVDivBpQbB1pp25IlgrNTa1EOVsX3KmkIlXTHhTz2DVwreSkdyrA3Zs41/s1600/Hypertension.+2000.jpg" imageanchor="1" style="margin-left: 1em; margin-right: 1em;"><img border="0" height="385" src="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEjlzqGbCymFwhydUXplkLK3EVGsNss2cTiahda9V3elP97_VZig8nd0PjUDRvW6RLUSCHxnJ-eXIuK0YQ5RmXJgVDivBpQbB1pp25IlgrNTa1EOVsX3KmkIlXTHhTz2DVwreSkdyrA3Zs41/s400/Hypertension.+2000.jpg" width="400" /></a></div>
<div>
<br /></div>
</div>
11jigenhttp://www.blogger.com/profile/03513633746083109180noreply@blogger.com0tag:blogger.com,1999:blog-2022612537151365301.post-31072658499053736572013-05-18T22:17:00.004+09:002013-05-18T22:17:55.042+09:00Differential activation of cardiac c-jun amino-terminal kinase and extracellular signal-regulated kinase in angiotensin II-mediated hypertension.<br />
<br />
<div class="cit" style="background-color: white; font-family: arial, helvetica, clean, sans-serif; font-size: 0.8465em; line-height: 1.45em;">
<span role="menubar">Circ Res.</span> 1998 Oct 5;83(7):752-60.</div>
<h1 style="background-color: white; font-family: arial, helvetica, clean, sans-serif; font-size: 1.231em; line-height: 1.125em; margin: 0.375em 0px;">
Differential activation of cardiac c-jun amino-terminal kinase and extracellular signal-regulated kinase in angiotensin II-mediated hypertension.</h1>
<div class="auths" style="background-color: white;">
<span style="font-family: arial, helvetica, clean, sans-serif;"><span style="font-size: 14.545454025268555px;">Yano M, <a href="http://shokei-kim-mitsuyama.blogspot.com/">Kim S</a>, Izumi Y, <a href="http://yamanaka-shinya.blogspot.com/">Yamanaka S</a> (</span><span style="font-size: 14.545454025268555px;"><a href="http://blog.goo.ne.jp/netsuzou/e/a703a56e46063cd81de556269b3cb3b9">山中伸弥</a></span></span><span style="font-family: arial, helvetica, clean, sans-serif; font-size: 14.545454025268555px;">), Iwao H.</span></div>
<div class="aff" style="background-color: white;">
<h3 class="label" style="color: #724128; font-family: arial, helvetica, clean, sans-serif; font-size: 1.0769em; height: 1px; left: -10000px; line-height: 1.2857; margin: 1.2856em 0px 0.6428em; overflow: hidden; position: absolute; top: auto; width: 1px;">
Source</h3>
<div style="font-family: arial, helvetica, clean, sans-serif; font-size: 0.8465em; line-height: 1.0915em; margin-bottom: 0.5em; margin-top: 0.5em;">
Department of Pharmacology, Osaka City University Medical School, Osaka, Japan.</div>
<div style="font-family: arial, helvetica, clean, sans-serif; font-size: 0.8465em; line-height: 1.0915em; margin-bottom: 0.5em; margin-top: 0.5em;">
<a href="http://www.ncbi.nlm.nih.gov/pubmed/9758646">http://www.ncbi.nlm.nih.gov/pubmed/9758646</a></div>
<div style="font-family: arial, helvetica, clean, sans-serif; font-size: 0.8465em; line-height: 1.0915em; margin-bottom: 0.5em; margin-top: 0.5em;">
<a href="http://circres.ahajournals.org/content/83/7/752.long">http://circres.ahajournals.org/content/83/7/752.long</a></div>
<div style="font-family: arial, helvetica, clean, sans-serif; font-size: 0.8465em; line-height: 1.0915em; margin-bottom: 0.5em; margin-top: 0.5em;">
<br /></div>
<div style="margin-bottom: 0.5em; margin-top: 0.5em;">
<div style="font-family: arial, helvetica, clean, sans-serif; line-height: 1.0915em;">
<span style="color: #38761d; font-family: 'Trebuchet MS', Trebuchet, Verdana, sans-serif; line-height: 18px;"><a href="http://circres.ahajournals.org/content/83/7/752/F1.large.jpg">Fig.1C</a> - The l</span><span style="color: #38761d; font-family: 'Times New Roman'; line-height: normal;">ane of "5min" is similar to the horizontally flipped image of </span><span style="color: #38761d; font-family: 'Times New Roman'; line-height: normal;">"3h</span><span style="color: #38761d; font-family: 'Times New Roman'; line-height: normal;">" lane</span><span style="color: #38761d; font-family: 'Times New Roman'; line-height: normal;">.</span></div>
<span style="font-family: Trebuchet MS, Trebuchet, Verdana, sans-serif;"><span style="line-height: 17.99715805053711px;">( <a href="http://circres.ahajournals.org/content/83/7/752/F1.large.jpg">Fig. 1C</a>の5 minと3hが、左右反転すると類似。一致はしない。 3hのp42ERKの左端の方にある白い帯はノイズだろうか。 )</span></span><br />
<span style="font-family: Trebuchet MS, Trebuchet, Verdana, sans-serif;"><span style="line-height: 17.99715805053711px;"><br /></span></span>
<div class="separator" style="clear: both; text-align: center;">
<a href="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEh5lvhEh7Pkoy7O6iv2ya5UlOis0htiYJ-jr6l1FKsO7iDaU2bJlBBd-XAgSuao3Hckhg1Lqeg20qjNGEQHEGzN0r9GDQHL_215GuDfDMmvErpQkpbOa9l5s6Z47iKB8D219sNiynUMMsTI/s1600/Circ+Res.+1998.jpg" imageanchor="1" style="margin-left: 1em; margin-right: 1em;"><img border="0" height="400" src="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEh5lvhEh7Pkoy7O6iv2ya5UlOis0htiYJ-jr6l1FKsO7iDaU2bJlBBd-XAgSuao3Hckhg1Lqeg20qjNGEQHEGzN0r9GDQHL_215GuDfDMmvErpQkpbOa9l5s6Z47iKB8D219sNiynUMMsTI/s400/Circ+Res.+1998.jpg" width="257" /></a></div>
<div>
<br /></div>
</div>
</div>
11jigenhttp://www.blogger.com/profile/03513633746083109180noreply@blogger.com0tag:blogger.com,1999:blog-2022612537151365301.post-65765581722921710252013-05-18T22:17:00.001+09:002013-05-18T22:17:36.348+09:00Cardiac mitogen-activated protein kinase activities are chronically increased in stroke-prone hypertensive rats.<br />
<span role="menubar" style="background-color: white; font-family: arial, helvetica, clean, sans-serif; font-size: 20px; line-height: 1.45em;">Hypertension.</span><span style="background-color: white; font-family: arial, helvetica, clean, sans-serif; font-size: 20px; line-height: 1.45em;"> 1998 Jan;31(1):50-6.</span><br />
<h1 style="background-color: white; font-family: arial, helvetica, clean, sans-serif; font-size: 1.231em; line-height: 1.125em; margin: 0.375em 0px;">
Cardiac mitogen-activated protein kinase activities are chronically increased in stroke-prone hypertensive rats.</h1>
<div class="auths" style="background-color: white;">
<span style="font-family: arial, helvetica, clean, sans-serif;"><span style="font-size: 20px;">Izumi Y, <a href="http://shokei-kim-mitsuyama.blogspot.com/">Kim S</a>, Murakami T, <a href="http://yamanaka-shinya.blogspot.com/">Yamanaka S</a> (<a href="http://blog.goo.ne.jp/netsuzou?fm=rss">山中伸弥</a>), Iwao H.</span></span></div>
<div class="aff" style="background-color: white;">
<h3 class="label" style="color: #724128; font-family: arial, helvetica, clean, sans-serif; font-size: 1.0769em; height: 1px; left: -10000px; line-height: 1.2857; margin: 1.2856em 0px 0.6428em; overflow: hidden; position: absolute; top: auto; width: 1px;">
Source</h3>
<div style="font-family: arial, helvetica, clean, sans-serif; font-size: 20px; line-height: 1.0915em; margin-bottom: 0.5em; margin-top: 0.5em;">
Department of Pharmacology, Osaka City University Medical School, Abeno, Osaka, Japan.</div>
<div style="font-family: arial, helvetica, clean, sans-serif; font-size: 20px; line-height: 1.0915em; margin-bottom: 0.5em; margin-top: 0.5em;">
<a href="http://www.ncbi.nlm.nih.gov/pubmed/9449390">http://www.ncbi.nlm.nih.gov/pubmed/9449390</a></div>
<div style="font-family: arial, helvetica, clean, sans-serif; font-size: 20px; line-height: 1.0915em; margin-bottom: 0.5em; margin-top: 0.5em;">
<a href="http://hyper.ahajournals.org/content/31/1/50.long">http://hyper.ahajournals.org/content/31/1/50.long</a></div>
<div style="font-family: arial, helvetica, clean, sans-serif; font-size: 20px; line-height: 1.0915em; margin-bottom: 0.5em; margin-top: 0.5em;">
<br /></div>
<div style="margin-bottom: 0.5em; margin-top: 0.5em;">
<span style="color: #38761d; font-family: arial, helvetica, clean, sans-serif;"><span style="font-size: 20px; line-height: 21.81818199157715px;"><a href="http://hyper.ahajournals.org/content/31/1/50/F5.large.jpg">Fig.5</a> - The left lane and right lane of </span></span><span style="color: #38761d; font-family: arial, helvetica, clean, sans-serif; font-size: 20px; line-height: 21.81818199157715px;">"</span><span style="color: #38761d; font-family: arial, helvetica, clean, sans-serif;"><span style="font-size: 20px; line-height: 21.81818199157715px;">S (SHRSP)</span></span><span style="color: #38761d; font-family: arial, helvetica, clean, sans-serif; font-size: 20px; line-height: 21.81818199157715px;">"</span><span style="color: #38761d; font-family: arial, helvetica, clean, sans-serif;"><span style="font-size: 20px; line-height: 21.81818199157715px;"> of </span></span><span style="color: #38761d; font-family: arial, helvetica, clean, sans-serif; font-size: 20px; line-height: 21.81818199157715px;">"24 wk"</span><span style="color: #38761d; font-family: arial, helvetica, clean, sans-serif; font-size: 20px; line-height: 21.81818199157715px;"> are similar. </span></div>
<div style="margin-bottom: 0.5em; margin-top: 0.5em;">
<span style="font-family: arial, helvetica, clean, sans-serif;"><span style="font-size: 20px; line-height: 21.81818199157715px;">( <a href="http://hyper.ahajournals.org/content/31/1/50/F5.large.jpg">Fig. 5</a>の24 wk、S(SHRSP)の2レーンが、レーン間で類似。一致はしない。 </span></span></div>
<div style="margin-bottom: 0.5em; margin-top: 0.5em;">
<span style="font-family: arial, helvetica, clean, sans-serif;"><span style="font-size: 20px; line-height: 21.81818199157715px;">特に、p55 JNKとp46 JNKの間の部分の一部が左のレーンでは存在しない。 )</span></span><br />
<span style="font-family: arial, helvetica, clean, sans-serif;"><span style="font-size: 20px; line-height: 21.81818199157715px;"><br /></span></span>
<div class="separator" style="clear: both; text-align: center;">
<a href="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEgFTO5xxp7JV3NODZW5zvA5DWYWY0We80e_s3xPpPOCuQsJDo0eVVhnAoHxIm1PaWTosPhSPTCuaVekS7DwMr_vXpuywQrG1yA3tJylzbQKLaNVQYAIQ4mXDzsCwxN_tLvOt4q9i6ye-S-N/s1600/Hypertension+1998+Fig5.jpg" imageanchor="1" style="margin-left: 1em; margin-right: 1em;"><img border="0" height="400" src="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEgFTO5xxp7JV3NODZW5zvA5DWYWY0We80e_s3xPpPOCuQsJDo0eVVhnAoHxIm1PaWTosPhSPTCuaVekS7DwMr_vXpuywQrG1yA3tJylzbQKLaNVQYAIQ4mXDzsCwxN_tLvOt4q9i6ye-S-N/s400/Hypertension+1998+Fig5.jpg" width="277" /></a></div>
<div>
<br /></div>
</div>
</div>
11jigenhttp://www.blogger.com/profile/03513633746083109180noreply@blogger.com0